TLR4+group 2 innate lymphoid cells contribute to persistent type 2 immunity in airway diseases

TLR4+group 2 innate lymphoid cells contribute to persistent type 2 immunity in airway diseases

Abstract Group 2 innate lymphoid cells (ILC2s) directly contribute to local inflammation in type 2 inflammatory airway diseases. Here, we identify ILC2 subsets by single cell RNA sequencing in chronic rhinosinusitis with nasal polyps (CRSwNP) and in a memory inflammatory mouse model. We find that to...

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Bibliographic Details
Main Authors: Yan Li, Zaichuan Wang, Su Duan, Xue Wang, Yuling Zhang, Claus Bachert, Nan Zhang, Wei Wang, Sun Ying, Feng Lan, Chengshuo Wang, Luo Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62532-0
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