SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILK
Objective: This study aimed to determine the presence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antigens and IgM and IgG antibodies in breast milk of mothers diagnosed with Coronavirus disease-19 (COVID-19). Methods: The study was conducted in 11 mother-child pairs. Breastfeedi...
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| Format: | Article |
| Language: | English |
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Istanbul University Press
2021-07-01
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| Series: | İstanbul Tıp Fakültesi Dergisi |
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| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/E968157465DC4EA3833705903474F063 |
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| author | Gonca Keskindemirci Nalan Karabayır Ayşe İstanbullu Tosun Selda Hançerli Törün Ceren Sultan Altay Muhammet Fatih Sebirli Özge Kaba Büşra Sultan Kibar Emine Gülbin Gökçay |
| author_facet | Gonca Keskindemirci Nalan Karabayır Ayşe İstanbullu Tosun Selda Hançerli Törün Ceren Sultan Altay Muhammet Fatih Sebirli Özge Kaba Büşra Sultan Kibar Emine Gülbin Gökçay |
| author_sort | Gonca Keskindemirci |
| collection | DOAJ |
| description | Objective: This study aimed to determine the presence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antigens and IgM and IgG antibodies in breast milk of mothers diagnosed with Coronavirus disease-19 (COVID-19). Methods: The study was conducted in 11 mother-child pairs. Breastfeeding mothers who were either positive according to a PCR test or those who were negative but had COVID symptoms were included in the study. Expressed milk was stored at -20/-80°C until analysis. Breastmilk SARS-CoV-2 antigens and IgM and IgG antibodies were measured. The infants were followed for at least 15 days. Results: SARS-CoV-2 PCR tests using a nasofarengeal swab was positive in 10 of 11 mothers. Nine mothers had symptoms of COVID-19. Breast milk samples were taken, on average, 15 days after symptom onset or a positive PCR result. SARS-CoV-2 PCR tests using a nasopharyngeal swab was positive in seven infants. The SARS-CoV-2 antigen was not detected in the breast milk of any of the mothers. However, SARS-CoV-2 IgG and IgM antibodies were detected in the breast milk of two mothers, who had a positive PCR test and experienced clinical symptoms. The children of these two mothers experienced no symptoms.Conclusion: Official institutions have recommended and supported breastfeeding during the SARS-CoV-2 pandemic. Our findings support this recommendation. The promotion and protection of breastfeeding under emergency conditions is of great importance for the health of children, mothers, and society. |
| format | Article |
| id | doaj-art-91413f12c83047c5afcb2e4fd7bdf171 |
| institution | Kabale University |
| issn | 1305-6441 |
| language | English |
| publishDate | 2021-07-01 |
| publisher | Istanbul University Press |
| record_format | Article |
| series | İstanbul Tıp Fakültesi Dergisi |
| spelling | doaj-art-91413f12c83047c5afcb2e4fd7bdf1712025-08-20T03:52:47ZengIstanbul University Pressİstanbul Tıp Fakültesi Dergisi1305-64412021-07-0184328729210.26650/IUITFD.2021.928835123456SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILKGonca Keskindemirci0https://orcid.org/0000-0003-1797-2802Nalan Karabayır1https://orcid.org/0000-0002-8003-1952Ayşe İstanbullu Tosun2https://orcid.org/0000-0003-3952-1914Selda Hançerli Törün3https://orcid.org/0000-0002-3216-2413Ceren Sultan Altay4https://orcid.org/0000-0002-5439-192XMuhammet Fatih Sebirli5https://orcid.org/0000-0001-6465-0449Özge Kaba6https://orcid.org/0000-0002-8381-3255Büşra Sultan Kibar7https://orcid.org/0000-0002-6535-1034Emine Gülbin Gökçay8https://orcid.org/0000-0003-1042-0407İstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Medipol Üniversitesi, Istanbul, Turkiyeİstanbul Medipol Üniversitesi, Istanbul, Turkiyeİstanbul Üniversitesi, İstanbul, Türkiyeİstanbul Medipol Üniversitesi, Istanbul, Turkiyeİstanbul Medipol Üniversitesi, Istanbul, Turkiyeİstanbul Üniversitesi, İstanbul, TürkiyeT.C. The Ministry of Health, Ankara, Turkiyeİstanbul Üniversitesi, İstanbul, TürkiyeObjective: This study aimed to determine the presence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antigens and IgM and IgG antibodies in breast milk of mothers diagnosed with Coronavirus disease-19 (COVID-19). Methods: The study was conducted in 11 mother-child pairs. Breastfeeding mothers who were either positive according to a PCR test or those who were negative but had COVID symptoms were included in the study. Expressed milk was stored at -20/-80°C until analysis. Breastmilk SARS-CoV-2 antigens and IgM and IgG antibodies were measured. The infants were followed for at least 15 days. Results: SARS-CoV-2 PCR tests using a nasofarengeal swab was positive in 10 of 11 mothers. Nine mothers had symptoms of COVID-19. Breast milk samples were taken, on average, 15 days after symptom onset or a positive PCR result. SARS-CoV-2 PCR tests using a nasopharyngeal swab was positive in seven infants. The SARS-CoV-2 antigen was not detected in the breast milk of any of the mothers. However, SARS-CoV-2 IgG and IgM antibodies were detected in the breast milk of two mothers, who had a positive PCR test and experienced clinical symptoms. The children of these two mothers experienced no symptoms.Conclusion: Official institutions have recommended and supported breastfeeding during the SARS-CoV-2 pandemic. Our findings support this recommendation. The promotion and protection of breastfeeding under emergency conditions is of great importance for the health of children, mothers, and society.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/E968157465DC4EA3833705903474F063breast milkcovid-19breastfeeding |
| spellingShingle | Gonca Keskindemirci Nalan Karabayır Ayşe İstanbullu Tosun Selda Hançerli Törün Ceren Sultan Altay Muhammet Fatih Sebirli Özge Kaba Büşra Sultan Kibar Emine Gülbin Gökçay SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILK İstanbul Tıp Fakültesi Dergisi breast milk covid-19 breastfeeding |
| title | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILK |
| title_full | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILK |
| title_fullStr | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILK |
| title_full_unstemmed | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILK |
| title_short | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 ANTIGENS AND ANTIBODIES IN BREAST MILK |
| title_sort | severe acute respiratory syndrome coronavirus 2 antigens and antibodies in breast milk |
| topic | breast milk covid-19 breastfeeding |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/E968157465DC4EA3833705903474F063 |
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