CD47 Blockade Inhibits Tumor Progression through Promoting Phagocytosis of Tumor Cells by M2 Polarized Macrophages in Endometrial Cancer
There are rapidly emerging efforts to explore tumor-associated macrophages (TAMs) as a tumor therapy target. Tumor cells express CD47, which can interact with the macrophages’ SIRPα transmitting a “don’t eat me” signal to macrophages. The expression of CD47 increases in various tumors to evade immun...
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| Main Authors: | Shenglan Gu, Ting Ni, Jing Wang, Yao Liu, Qiong Fan, Yiwei Wang, Ting Huang, Yiwei Chu, Xiao Sun, Yudong Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2018/6156757 |
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