Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care Center

Background: Pleural effusion is the collection of fluid in the pleural space. Divided into exudative and transudative type. This study aims to find the clinical profile, etiology, and outcome of the patients with pleural effusion. Materials and Methods: This was a prospective descriptive study do...

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Main Authors: Arun Kumar Mahato, Saurav Poudel, Bivusha Parajuli, Anil Mahato, Niranjan KC, Manoj Kumar Thakur, Karuna Bhatta, Ram Hari Ghimire
Format: Article
Language:English
Published: Nobel Medical College Teaching Hospital 2024-12-01
Series:Journal of Nobel Medical College
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Online Access:https://www.nepjol.info/index.php/JoNMC/article/view/74399
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author Arun Kumar Mahato
Saurav Poudel
Bivusha Parajuli
Anil Mahato
Niranjan KC
Manoj Kumar Thakur
Karuna Bhatta
Ram Hari Ghimire
author_facet Arun Kumar Mahato
Saurav Poudel
Bivusha Parajuli
Anil Mahato
Niranjan KC
Manoj Kumar Thakur
Karuna Bhatta
Ram Hari Ghimire
author_sort Arun Kumar Mahato
collection DOAJ
description Background: Pleural effusion is the collection of fluid in the pleural space. Divided into exudative and transudative type. This study aims to find the clinical profile, etiology, and outcome of the patients with pleural effusion. Materials and Methods: This was a prospective descriptive study done in a tertiary center from 8th March 2024 to 7th September 2024. Ethical approval was taken from the institutional review committee (Ref:12/2024). A total of 60 adult patients with new onset pleural effusion were included in the study, with their demographics, clinical profile, and immediate outcome being studied. Results: A total of 60 patients were included, the male-to-female ratio was 1.14: 1, with the mean age being 46.31 ± 9.62 years, with 32 (53.33%) patients of the age group 40-59 years. Tuberculosis was the most common etiology of pleural effusion occurring in 21 (35%) cases, followed by para-pneumonic effusion in 16 (26.67%) and congestive cardiac failure in 9 (15%). Shortness of breath was the most common symptom seen in 43 (71.67%) cases, while lymphocytosis was the most common hematological manifestation in 46(76.67%). The mean Adenosine Deaminase level was 67.21 ± 24.21 International Units /Litre. Two (3.33%) cases ended in mortality. The mean hospital stay was 8.86 ± 3.31 days. A rare occurrence of re-expansion pulmonary edema was observed. Conclusion: The most common cause of pleural effusion in our setting is tuberculosis followed by para-pneumonic effusion, with 40-59 years of age being the most common age group. Adenosine deaminase level is a reliable indicator of tubercular pleural effusion.
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spelling doaj-art-912e843473ad4f90954e29b00c8d68552025-08-20T03:10:47ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2024-12-01132141910.3126/jonmc.v13i2.74399101545Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care CenterArun Kumar Mahato0https://orcid.org/0000-0001-6224-7226Saurav Poudel1Bivusha Parajuli2Anil Mahato3Niranjan KC4Manoj Kumar Thakur5Karuna Bhatta6Ram Hari Ghimire7Department of Pulmonary, Critical Care and Sleep Medicine, Nobel Medical College Teaching Hospital, Biratnagar, NepalDepartment of Pulmonary, Critical Care and Sleep Medicine, Nobel Medical College Teaching Hospital, Biratnagar, NepalDepartment of Pulmonary, Critical Care and Sleep Medicine, Nobel Medical College Teaching Hospital, Biratnagar, NepalDepartment of Community Medicine, Kathmandu Medical College, Sinamangal, NepalDepartment of Internal Medicine, Nobel Medical College Teaching Hospital, Biratnagar, NepalDepartment of Internal Medicine, Koshi Zonal Hospital, Biratnagar, NepalDepartment of Pulmonary, Critical Care and Sleep Medicine, Nobel Medical College Teaching Hospital, Biratnagar, NepalDepartment of Pulmonary, Critical Care and Sleep Medicine, Nobel Medical College Teaching Hospital, Biratnagar, NepalBackground: Pleural effusion is the collection of fluid in the pleural space. Divided into exudative and transudative type. This study aims to find the clinical profile, etiology, and outcome of the patients with pleural effusion. Materials and Methods: This was a prospective descriptive study done in a tertiary center from 8th March 2024 to 7th September 2024. Ethical approval was taken from the institutional review committee (Ref:12/2024). A total of 60 adult patients with new onset pleural effusion were included in the study, with their demographics, clinical profile, and immediate outcome being studied. Results: A total of 60 patients were included, the male-to-female ratio was 1.14: 1, with the mean age being 46.31 ± 9.62 years, with 32 (53.33%) patients of the age group 40-59 years. Tuberculosis was the most common etiology of pleural effusion occurring in 21 (35%) cases, followed by para-pneumonic effusion in 16 (26.67%) and congestive cardiac failure in 9 (15%). Shortness of breath was the most common symptom seen in 43 (71.67%) cases, while lymphocytosis was the most common hematological manifestation in 46(76.67%). The mean Adenosine Deaminase level was 67.21 ± 24.21 International Units /Litre. Two (3.33%) cases ended in mortality. The mean hospital stay was 8.86 ± 3.31 days. A rare occurrence of re-expansion pulmonary edema was observed. Conclusion: The most common cause of pleural effusion in our setting is tuberculosis followed by para-pneumonic effusion, with 40-59 years of age being the most common age group. Adenosine deaminase level is a reliable indicator of tubercular pleural effusion.https://www.nepjol.info/index.php/JoNMC/article/view/74399pleurapleural effusionpneumoniatuberculosis
spellingShingle Arun Kumar Mahato
Saurav Poudel
Bivusha Parajuli
Anil Mahato
Niranjan KC
Manoj Kumar Thakur
Karuna Bhatta
Ram Hari Ghimire
Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care Center
Journal of Nobel Medical College
pleura
pleural effusion
pneumonia
tuberculosis
title Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care Center
title_full Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care Center
title_fullStr Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care Center
title_full_unstemmed Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care Center
title_short Clinical Presentations and Outcome of Patients with Pleural Effusion: A Study at a Tertiary Care Center
title_sort clinical presentations and outcome of patients with pleural effusion a study at a tertiary care center
topic pleura
pleural effusion
pneumonia
tuberculosis
url https://www.nepjol.info/index.php/JoNMC/article/view/74399
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