Qu-zhuo-tong-bi decoction exerts gouty arthritis therapy by skewing macrophage polarization through butanoate metabolism

Qu-zhuo-tong-bi decoction exerts gouty arthritis therapy by skewing macrophage polarization through butanoate metabolism

Abstract Background Qu-zhuo-tong-bi decoction (QZTBD), a traditional Chinese medicine (TCM), has demonstrated efficacy in the treatment of gouty arthritis. However, to date, the precise pharmacological mechanisms remain unclear. Purpose The study aims to ascertain the therapeutic effects and the und...

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Bibliographic Details
Main Authors: Siyue Song, Xianghui Wen, Fusen Chen, Jiatao Li, Kaiyue Shi, Yu Lou, Anyi Xu, Chengping Wen, Tiejuan Shao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Chinese Medicine
Subjects:
Qu-zhuo-tong-bi decoction
Gouty arthritis
Gut microbiome
Butanoate metabolism
Macrophage polarization
Glycolysis
Online Access:https://doi.org/10.1186/s13020-025-01162-6
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