Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
Rectal cancer is one of the most prevalent malignancies worldwide, and the introduction of an endoscopic submucosal dissection (ESD) has offered minimally invasive management for early colorectal cancers. On the other hand, a post-ESD pathological examination showed that the risk of lymph node metas...
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Jin Publishing & Printing Co.
2024-11-01
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Series: | The Korean Journal of Gastroenterology |
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Online Access: | https://www.kjg.or.kr/journal/view.html?uid=6063&vmd=Full |
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author | Ji Hye Park Jae Hyun Kim Sung Hyun Ko Seun Ja Park |
author_facet | Ji Hye Park Jae Hyun Kim Sung Hyun Ko Seun Ja Park |
author_sort | Ji Hye Park |
collection | DOAJ |
description | Rectal cancer is one of the most prevalent malignancies worldwide, and the introduction of an endoscopic submucosal dissection (ESD) has offered minimally invasive management for early colorectal cancers. On the other hand, a post-ESD pathological examination showed that the risk of lymph node metastasis increases with deep submucosal (SM) invasion, positive lymphovascular invasion, grade 2/3 tumor budding, and certain histological types. An intestinal resection with a lymph node dissection is recommended in
these cases, and chemoradiotherapy (CRT) is also effective adjuvant therapy. This paper reports a case series of patients who underwent ESD for rectal cancer and received concurrent CRT because of pathologically confirmed deep SM invasion. |
format | Article |
id | doaj-art-9100f909133e4fe787e287f75a1ee588 |
institution | Kabale University |
issn | 1598-9992 2233-6869 |
language | English |
publishDate | 2024-11-01 |
publisher | Jin Publishing & Printing Co. |
record_format | Article |
series | The Korean Journal of Gastroenterology |
spelling | doaj-art-9100f909133e4fe787e287f75a1ee5882025-01-03T05:17:59ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692024-11-0184523023410.4166/kjg.2024.088Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case SeriesJi Hye Park0Jae Hyun Kim1Sung Hyun Ko2Seun Ja Park3https://orcid.org/0000-0003-3217-5115Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDivision of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDivision of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDivision of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaRectal cancer is one of the most prevalent malignancies worldwide, and the introduction of an endoscopic submucosal dissection (ESD) has offered minimally invasive management for early colorectal cancers. On the other hand, a post-ESD pathological examination showed that the risk of lymph node metastasis increases with deep submucosal (SM) invasion, positive lymphovascular invasion, grade 2/3 tumor budding, and certain histological types. An intestinal resection with a lymph node dissection is recommended in these cases, and chemoradiotherapy (CRT) is also effective adjuvant therapy. This paper reports a case series of patients who underwent ESD for rectal cancer and received concurrent CRT because of pathologically confirmed deep SM invasion.https://www.kjg.or.kr/journal/view.html?uid=6063&vmd=Fullrectal neoplasmsendoscopic mucosal resectionchemoradiotherapy |
spellingShingle | Ji Hye Park Jae Hyun Kim Sung Hyun Ko Seun Ja Park Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series The Korean Journal of Gastroenterology rectal neoplasms endoscopic mucosal resection chemoradiotherapy |
title | Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series |
title_full | Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series |
title_fullStr | Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series |
title_full_unstemmed | Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series |
title_short | Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series |
title_sort | combining endoscopic submucosal dissection and adjuvant chemoradiotherapy or radiotherapy for effective management of rectal cancer with deep submucosal invasion a case series |
topic | rectal neoplasms endoscopic mucosal resection chemoradiotherapy |
url | https://www.kjg.or.kr/journal/view.html?uid=6063&vmd=Full |
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