Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series

Rectal cancer is one of the most prevalent malignancies worldwide, and the introduction of an endoscopic submucosal dissection (ESD) has offered minimally invasive management for early colorectal cancers. On the other hand, a post-ESD pathological examination showed that the risk of lymph node metas...

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Main Authors: Ji Hye Park, Jae Hyun Kim, Sung Hyun Ko, Seun Ja Park
Format: Article
Language:English
Published: Jin Publishing & Printing Co. 2024-11-01
Series:The Korean Journal of Gastroenterology
Subjects:
Online Access:https://www.kjg.or.kr/journal/view.html?uid=6063&vmd=Full
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author Ji Hye Park
Jae Hyun Kim
Sung Hyun Ko
Seun Ja Park
author_facet Ji Hye Park
Jae Hyun Kim
Sung Hyun Ko
Seun Ja Park
author_sort Ji Hye Park
collection DOAJ
description Rectal cancer is one of the most prevalent malignancies worldwide, and the introduction of an endoscopic submucosal dissection (ESD) has offered minimally invasive management for early colorectal cancers. On the other hand, a post-ESD pathological examination showed that the risk of lymph node metastasis increases with deep submucosal (SM) invasion, positive lymphovascular invasion, grade 2/3 tumor budding, and certain histological types. An intestinal resection with a lymph node dissection is recommended in these cases, and chemoradiotherapy (CRT) is also effective adjuvant therapy. This paper reports a case series of patients who underwent ESD for rectal cancer and received concurrent CRT because of pathologically confirmed deep SM invasion.
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institution Kabale University
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publishDate 2024-11-01
publisher Jin Publishing & Printing Co.
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series The Korean Journal of Gastroenterology
spelling doaj-art-9100f909133e4fe787e287f75a1ee5882025-01-03T05:17:59ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692024-11-0184523023410.4166/kjg.2024.088Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case SeriesJi Hye Park0Jae Hyun Kim1Sung Hyun Ko2Seun Ja Park3https://orcid.org/0000-0003-3217-5115Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDivision of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDivision of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaDivision of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaRectal cancer is one of the most prevalent malignancies worldwide, and the introduction of an endoscopic submucosal dissection (ESD) has offered minimally invasive management for early colorectal cancers. On the other hand, a post-ESD pathological examination showed that the risk of lymph node metastasis increases with deep submucosal (SM) invasion, positive lymphovascular invasion, grade 2/3 tumor budding, and certain histological types. An intestinal resection with a lymph node dissection is recommended in these cases, and chemoradiotherapy (CRT) is also effective adjuvant therapy. This paper reports a case series of patients who underwent ESD for rectal cancer and received concurrent CRT because of pathologically confirmed deep SM invasion.https://www.kjg.or.kr/journal/view.html?uid=6063&vmd=Fullrectal neoplasmsendoscopic mucosal resectionchemoradiotherapy
spellingShingle Ji Hye Park
Jae Hyun Kim
Sung Hyun Ko
Seun Ja Park
Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
The Korean Journal of Gastroenterology
rectal neoplasms
endoscopic mucosal resection
chemoradiotherapy
title Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
title_full Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
title_fullStr Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
title_full_unstemmed Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
title_short Combining Endoscopic Submucosal Dissection and Adjuvant Chemoradiotherapy or Radiotherapy for Effective Management of Rectal Cancer with Deep Submucosal Invasion: A Case Series
title_sort combining endoscopic submucosal dissection and adjuvant chemoradiotherapy or radiotherapy for effective management of rectal cancer with deep submucosal invasion a case series
topic rectal neoplasms
endoscopic mucosal resection
chemoradiotherapy
url https://www.kjg.or.kr/journal/view.html?uid=6063&vmd=Full
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