Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report
Syringoid eccrine carcinoma of nipple is an extremely rare neoplasm of adnexal origin with variable clinical appearance and diverse histologic findings. Syringoid eccrine carcinoma (SEC) is often a diagnostic dilemma due to its morphology and presentation. Usually, these malignancies arise as non-ul...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-04-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_716_23 |
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| author | Mukund Sable Nibedita Sahoo Chinamyee Panigrahi Pritinanda Mishra Pradeep Kumar |
| author_facet | Mukund Sable Nibedita Sahoo Chinamyee Panigrahi Pritinanda Mishra Pradeep Kumar |
| author_sort | Mukund Sable |
| collection | DOAJ |
| description | Syringoid eccrine carcinoma of nipple is an extremely rare neoplasm of adnexal origin with variable clinical appearance and diverse histologic findings. Syringoid eccrine carcinoma (SEC) is often a diagnostic dilemma due to its morphology and presentation. Usually, these malignancies arise as non-ulcerated nodules or plaques in the head & neck region including the trunk. They are locally aggressive and have an infiltrative growth pattern with a propensity for metastasis. SEC is characterized by syringoma-like tadpole morphology with ductular differentiation and predominant desmoplasia. Immunostaining in SEC is variable and this variability is believed to arise from the tumor’s ability to differentiate along multiple routes including sweat secretory and or ductal differentiation. Here we present a rare case of SEC/ syringomatous carcinoma of nipple in a 51-year-old male breast with associated axillary lymph node metastasis. As per English literature, this is the second case of SEC in nipple of male patient. |
| format | Article |
| id | doaj-art-90fb1426d1144c58a55ddb2e313bc6c8 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-90fb1426d1144c58a55ddb2e313bc6c82025-02-07T13:58:50ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-04-0167240140410.4103/ijpm.ijpm_716_23Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case reportMukund SableNibedita SahooChinamyee PanigrahiPritinanda MishraPradeep KumarSyringoid eccrine carcinoma of nipple is an extremely rare neoplasm of adnexal origin with variable clinical appearance and diverse histologic findings. Syringoid eccrine carcinoma (SEC) is often a diagnostic dilemma due to its morphology and presentation. Usually, these malignancies arise as non-ulcerated nodules or plaques in the head & neck region including the trunk. They are locally aggressive and have an infiltrative growth pattern with a propensity for metastasis. SEC is characterized by syringoma-like tadpole morphology with ductular differentiation and predominant desmoplasia. Immunostaining in SEC is variable and this variability is believed to arise from the tumor’s ability to differentiate along multiple routes including sweat secretory and or ductal differentiation. Here we present a rare case of SEC/ syringomatous carcinoma of nipple in a 51-year-old male breast with associated axillary lymph node metastasis. As per English literature, this is the second case of SEC in nipple of male patient.https://journals.lww.com/10.4103/ijpm.ijpm_716_23histomorphologyimmunohistochemistrynipplesyringoid eccrine carcinoma |
| spellingShingle | Mukund Sable Nibedita Sahoo Chinamyee Panigrahi Pritinanda Mishra Pradeep Kumar Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report Indian Journal of Pathology and Microbiology histomorphology immunohistochemistry nipple syringoid eccrine carcinoma |
| title | Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report |
| title_full | Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report |
| title_fullStr | Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report |
| title_full_unstemmed | Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report |
| title_short | Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report |
| title_sort | syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis a case report |
| topic | histomorphology immunohistochemistry nipple syringoid eccrine carcinoma |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_716_23 |
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