Central motor conduction in human chronic Chagas' disease
The possible involvement of spinal alpha motor neurons, dorsal root ganglia and sensory fibers in human chronic Chagas' disease was previously demonstrated. More recently neuropsychological and sensory evoked potentials studies suggest the existence of central nervous system abnormalities in th...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
1994-03-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1994000100005&lng=en&tlng=en |
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| author | M.J. Segura O.M. Genovese Elsa Segura Olga P. Sanz R.E.P. Sica |
| author_facet | M.J. Segura O.M. Genovese Elsa Segura Olga P. Sanz R.E.P. Sica |
| author_sort | M.J. Segura |
| collection | DOAJ |
| description | The possible involvement of spinal alpha motor neurons, dorsal root ganglia and sensory fibers in human chronic Chagas' disease was previously demonstrated. More recently neuropsychological and sensory evoked potentials studies suggest the existence of central nervous system abnormalities in these patients. We assessed the state of central motor pathways in 46 patients with chronic Chagas' disease and 30 healthy volunteers by means of percutaneous cortical and spinal electrical stimulation. No significative slowness in pyramidal tracts (PT) conduction was found when comparing both groups. Neither any individual patient exhibited abnormally delayed PT conduction values beyond the upper normal limit of the healthy volunteers. These results suggest that, in contrast with other neural systems, the large myelinated PT fibers are usually spared in human chronic Chagas' disease. |
| format | Article |
| id | doaj-art-90f985aeaa984791a424d512bfda6065 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 1994-03-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-90f985aeaa984791a424d512bfda60652025-08-20T01:58:27ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271994-03-01521293110.1590/S0004-282X1994000100005S0004-282X1994000100005Central motor conduction in human chronic Chagas' diseaseM.J. Segura0O.M. Genovese1Elsa Segura2Olga P. Sanz3R.E.P. SicaUniversidad de Buenos AiresUniversidad de Buenos AiresUniversidad de Buenos AiresUniversidad de Buenos AiresThe possible involvement of spinal alpha motor neurons, dorsal root ganglia and sensory fibers in human chronic Chagas' disease was previously demonstrated. More recently neuropsychological and sensory evoked potentials studies suggest the existence of central nervous system abnormalities in these patients. We assessed the state of central motor pathways in 46 patients with chronic Chagas' disease and 30 healthy volunteers by means of percutaneous cortical and spinal electrical stimulation. No significative slowness in pyramidal tracts (PT) conduction was found when comparing both groups. Neither any individual patient exhibited abnormally delayed PT conduction values beyond the upper normal limit of the healthy volunteers. These results suggest that, in contrast with other neural systems, the large myelinated PT fibers are usually spared in human chronic Chagas' disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1994000100005&lng=en&tlng=enenfermedad de Chagas cronicasistema nervioso centralpotenciales evocados motores |
| spellingShingle | M.J. Segura O.M. Genovese Elsa Segura Olga P. Sanz R.E.P. Sica Central motor conduction in human chronic Chagas' disease Arquivos de Neuro-Psiquiatria enfermedad de Chagas cronica sistema nervioso central potenciales evocados motores |
| title | Central motor conduction in human chronic Chagas' disease |
| title_full | Central motor conduction in human chronic Chagas' disease |
| title_fullStr | Central motor conduction in human chronic Chagas' disease |
| title_full_unstemmed | Central motor conduction in human chronic Chagas' disease |
| title_short | Central motor conduction in human chronic Chagas' disease |
| title_sort | central motor conduction in human chronic chagas disease |
| topic | enfermedad de Chagas cronica sistema nervioso central potenciales evocados motores |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1994000100005&lng=en&tlng=en |
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