Heterozygous deletion of exon 17 of the Kit gene impairs mouse spermatogenesis by attenuating MAPK-ERK signaling

Heterozygous deletion of exon 17 of the Kit gene impairs mouse spermatogenesis by attenuating MAPK-ERK signaling

Abstract Background A splice mutation that causes skipping of exon 17 in the KIT gene is a major reason for the dominant white phenotype of pigs. Exon 17 of the KIT gene may be related to differences in testis size and sperm quality among different pig breeds. Investigating the effects of exon 17 of...

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Bibliographic Details
Main Authors: Siyuan Lin, Min Yang, Weipeng Zhu, Changqi Yang, Yaosheng Chen, Peiqing Cong, Xiaohong Liu, Zuyong He
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Biological Research
Subjects:
Kit
Exon 17
Testicular development
Spermatogenesis
Online Access:https://doi.org/10.1186/s40659-025-00609-2
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