The relationship between rheumatoid arthritis (RA) and psychiatric disorder
Rheumatoid arthritis (RA) is a chronic autoimmune disease that has a destructive effect on the joints, but also leads to many systemic complications, including mental disorders. This review will present the co-occurrence of mood disorders, such as depression, anxiety and cognitive disorders, in pat...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-07-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/61176 |
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| author | Monika Kaźmierczak Oskar Tudaj Wiktoria Kalas Krzysztof Sajewicz Julia Dulęba Julia Kalisiak Mikołaj Musiał Maciej Hobot Aleksandra Mazur Filip Kin |
| author_facet | Monika Kaźmierczak Oskar Tudaj Wiktoria Kalas Krzysztof Sajewicz Julia Dulęba Julia Kalisiak Mikołaj Musiał Maciej Hobot Aleksandra Mazur Filip Kin |
| author_sort | Monika Kaźmierczak |
| collection | DOAJ |
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Rheumatoid arthritis (RA) is a chronic autoimmune disease that has a destructive effect on the joints, but also leads to many systemic complications, including mental disorders. This review will present the co-occurrence of mood disorders, such as depression, anxiety and cognitive disorders, in patients with RA and analyze the potential pathophysiological mechanisms. The impact of chronic inflammation and proinflammatory cytokines (IL-6, IL-1β, TNF-α) on the central nervous system and the hypothalamic-pituitary-adrenal axis (HPA) will be discussed. When rheumatoid arthritis (RA) is accompanied by mental health disorders, treatment methods used for RA may be less effective. This can make the condition harder to manage, increasing pain and reducing the quality of life. Additionally, the paper will present the impact of pain, fatigue and reduced physical fitness on the deterioration of the mental health of patients. In addition to the pharmacological treatment used for RA, which is also not neutral to patient’s health, additional therapeutic options such as psychological interventions will be discussed. Considering both somatic and psychological aspects, an interdisciplinary approach to the treatment of patients with RA is very important.
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| format | Article |
| id | doaj-art-90f3cf7c1d954f3f95a2f853f5e3752a |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-90f3cf7c1d954f3f95a2f853f5e3752a2025-08-20T03:31:07ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-07-014310.12775/QS.2025.43.61176The relationship between rheumatoid arthritis (RA) and psychiatric disorderMonika Kaźmierczak0https://orcid.org/0009-0005-8868-8368Oskar Tudaj1https://orcid.org/0009-0003-6934-459XWiktoria Kalas2https://orcid.org/0009-0001-5051-1365Krzysztof Sajewicz3https://orcid.org/0009-0007-2274-400XJulia Dulęba4https://orcid.org/0009-0009-1465-0809Julia Kalisiak5https://orcid.org/0009-0002-2432-0773Mikołaj Musiał6https://orcid.org/0009-0007-3113-8677Maciej Hobot7https://orcid.org/0009-0001-0087-6171Aleksandra Mazur8https://orcid.org/0009-0001-5037-0080Filip Kin9https://orcid.org/0009-0008-9017-2901Independent Public Complex of Health Care Facilities of the Ministry of Interior and Administration in PoznańSamodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa Spraw Wewnętrznych i Administracji w Poznaniu im. prof. Ludwika BierkowskiegoUniwersytet ZielonogórskiUniversity Clinical Hospital in PoznańUniversity Clinical Hospital in PoznańUniversity of Zielona Góra; Licealna Str. 9, 65-417 Zielona Góra, PolandIndependent Public Complex of Health Care Facilities of the Ministry of Interior and Administration in Poznań, Dojazd Str. 34, 60-631 Poznań, Poland University Clinical Hospital in Poznań; Przybyszewskiego 49, 60-355 Poznań, Poland; University Clinical Hospital in Poznań; Przybyszewskiego 49, 60-355 Poznań, Poland; University Clinical Hospital in Poznań, Przybyszewskiego 49, 60-355 Poznań, Poland Rheumatoid arthritis (RA) is a chronic autoimmune disease that has a destructive effect on the joints, but also leads to many systemic complications, including mental disorders. This review will present the co-occurrence of mood disorders, such as depression, anxiety and cognitive disorders, in patients with RA and analyze the potential pathophysiological mechanisms. The impact of chronic inflammation and proinflammatory cytokines (IL-6, IL-1β, TNF-α) on the central nervous system and the hypothalamic-pituitary-adrenal axis (HPA) will be discussed. When rheumatoid arthritis (RA) is accompanied by mental health disorders, treatment methods used for RA may be less effective. This can make the condition harder to manage, increasing pain and reducing the quality of life. Additionally, the paper will present the impact of pain, fatigue and reduced physical fitness on the deterioration of the mental health of patients. In addition to the pharmacological treatment used for RA, which is also not neutral to patient’s health, additional therapeutic options such as psychological interventions will be discussed. Considering both somatic and psychological aspects, an interdisciplinary approach to the treatment of patients with RA is very important. https://apcz.umk.pl/QS/article/view/61176rheumatoid arthritispsychiatric disordersdepressionanxiety |
| spellingShingle | Monika Kaźmierczak Oskar Tudaj Wiktoria Kalas Krzysztof Sajewicz Julia Dulęba Julia Kalisiak Mikołaj Musiał Maciej Hobot Aleksandra Mazur Filip Kin The relationship between rheumatoid arthritis (RA) and psychiatric disorder Quality in Sport rheumatoid arthritis psychiatric disorders depression anxiety |
| title | The relationship between rheumatoid arthritis (RA) and psychiatric disorder |
| title_full | The relationship between rheumatoid arthritis (RA) and psychiatric disorder |
| title_fullStr | The relationship between rheumatoid arthritis (RA) and psychiatric disorder |
| title_full_unstemmed | The relationship between rheumatoid arthritis (RA) and psychiatric disorder |
| title_short | The relationship between rheumatoid arthritis (RA) and psychiatric disorder |
| title_sort | relationship between rheumatoid arthritis ra and psychiatric disorder |
| topic | rheumatoid arthritis psychiatric disorders depression anxiety |
| url | https://apcz.umk.pl/QS/article/view/61176 |
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