Promoting vascular stability through Src inhibition and Tie2 activation: A model-based analysis
Summary: Dysregulated angiogenesis signaling leads to pathological vascular growth and leakage, and is a hallmark of many diseases including cancer and ocular diseases. In peripheral arterial disease, the concomitant increase in vascular permeability presents significant challenges in therapeutic ef...
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| Main Authors: | Yu Zhang, Christopher D. Kontos, Brian H. Annex, Aleksander S. Popel |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225008867 |
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