The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania major

Conclusion: IVE has shown significant efficacy in accelerating the healing process of wounds related to leishmaniasis. In addition, the administration of this medication has triggered a strong immune response, marked by activation of T helper 1 (Th1) and Th17 cells while also modulating Th2 response...

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Main Authors: Abdolbaset Rahmani, Nahid Maspi, Hamid Hasanpour, Shahab Falahi, Tooran Nayeri, Razi Naserifar
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/jotm/5579789
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author Abdolbaset Rahmani
Nahid Maspi
Hamid Hasanpour
Shahab Falahi
Tooran Nayeri
Razi Naserifar
author_facet Abdolbaset Rahmani
Nahid Maspi
Hamid Hasanpour
Shahab Falahi
Tooran Nayeri
Razi Naserifar
author_sort Abdolbaset Rahmani
collection DOAJ
description Conclusion: IVE has shown significant efficacy in accelerating the healing process of wounds related to leishmaniasis. In addition, the administration of this medication has triggered a strong immune response, marked by activation of T helper 1 (Th1) and Th17 cells while also modulating Th2 responses.
format Article
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institution Kabale University
issn 1687-9694
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Journal of Tropical Medicine
spelling doaj-art-90db3039cc69434c8ba9063102c01db12025-08-25T00:00:02ZengWileyJournal of Tropical Medicine1687-96942025-01-01202510.1155/jotm/5579789The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania majorAbdolbaset Rahmani0Nahid Maspi1Hamid Hasanpour2Shahab Falahi3Tooran Nayeri4Razi Naserifar5Department of ParasitologyDepartment of ParasitologyDepartment of ParasitologyZoonotic Diseases Research CenterInfectious and Tropical Diseases Research CenterDepartment of ParasitologyConclusion: IVE has shown significant efficacy in accelerating the healing process of wounds related to leishmaniasis. In addition, the administration of this medication has triggered a strong immune response, marked by activation of T helper 1 (Th1) and Th17 cells while also modulating Th2 responses.http://dx.doi.org/10.1155/jotm/5579789
spellingShingle Abdolbaset Rahmani
Nahid Maspi
Hamid Hasanpour
Shahab Falahi
Tooran Nayeri
Razi Naserifar
The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania major
Journal of Tropical Medicine
title The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania major
title_full The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania major
title_fullStr The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania major
title_full_unstemmed The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania major
title_short The Impact of Ivermectin on Immune Response and Wound Healing in a Mouse Model Infected With Leishmania major
title_sort impact of ivermectin on immune response and wound healing in a mouse model infected with leishmania major
url http://dx.doi.org/10.1155/jotm/5579789
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