Analysis method and experimental conditions affect computed circadian phase from melatonin data.

Analysis method and experimental conditions affect computed circadian phase from melatonin data.

Accurate determination of circadian phase is necessary for research and clinical purposes because of the influence of the master circadian pacemaker on multiple physiologic functions. Melatonin is presently the most accurate marker of the activity of the human circadian pacemaker. Current methods of...

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Bibliographic Details
Main Authors: Hadassa Klerman, Melissa A St Hilaire, Richard E Kronauer, Joshua J Gooley, Claude Gronfier, Joseph T Hull, Steven W Lockley, Nayantara Santhi, Wei Wang, Elizabeth B Klerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0033836&type=printable
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