Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ Disease

Purpose. To report a case of isolated superior oblique muscle swelling causing acute vertical strabismus in Graves’ disease. Case. A 26-year-old woman with a 1-month history of misalignment of the right eye and diplopia was referred to us. Her visual acuity and intraocular pressures were normal in b...

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Main Authors: Keiichi Aomatsu, Shunji Kusaka
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2020/8829655
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author Keiichi Aomatsu
Shunji Kusaka
author_facet Keiichi Aomatsu
Shunji Kusaka
author_sort Keiichi Aomatsu
collection DOAJ
description Purpose. To report a case of isolated superior oblique muscle swelling causing acute vertical strabismus in Graves’ disease. Case. A 26-year-old woman with a 1-month history of misalignment of the right eye and diplopia was referred to us. Her visual acuity and intraocular pressures were normal in both eyes, but eye movement tests showed clear misalignment of her right eye. Antibody tests for myasthenia gravis were negative. However, blood tests revealed abnormal levels of thyroid-related factors, such as decreased thyroid-stimulating hormone, elevated free T3 and T4, and elevated anti-thyroid-stimulating hormone receptor antibody. We performed magnetic resonance imaging (MRI), which showed slight enlargement of the left superior oblique muscle. The patient was eventually diagnosed with Graves’ disease with superior oblique muscle involvement and underwent a thyroidectomy. Three months postoperatively, her diplopia and abnormal eye movements had substantially resolved. Conclusion. Isolated superior oblique muscle involvement may be a presenting symptom of Graves’ disease. It should be taken into consideration that, in the early stages of thyroid-associated ophthalmopathy (TAO) in adults, only the superior oblique muscle may be enlarged.
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spelling doaj-art-90cfb48f8e2e40f8957b37596787a0fc2025-08-20T02:09:44ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302020-01-01202010.1155/2020/88296558829655Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ DiseaseKeiichi Aomatsu0Shunji Kusaka1Department of Ophthalmology, Nara Hospital, Kindai University Faculty of Medicine, Nara, JapanDepartment of Ophthalmology, Kindai University Faculty of Medicine, Osaka, JapanPurpose. To report a case of isolated superior oblique muscle swelling causing acute vertical strabismus in Graves’ disease. Case. A 26-year-old woman with a 1-month history of misalignment of the right eye and diplopia was referred to us. Her visual acuity and intraocular pressures were normal in both eyes, but eye movement tests showed clear misalignment of her right eye. Antibody tests for myasthenia gravis were negative. However, blood tests revealed abnormal levels of thyroid-related factors, such as decreased thyroid-stimulating hormone, elevated free T3 and T4, and elevated anti-thyroid-stimulating hormone receptor antibody. We performed magnetic resonance imaging (MRI), which showed slight enlargement of the left superior oblique muscle. The patient was eventually diagnosed with Graves’ disease with superior oblique muscle involvement and underwent a thyroidectomy. Three months postoperatively, her diplopia and abnormal eye movements had substantially resolved. Conclusion. Isolated superior oblique muscle involvement may be a presenting symptom of Graves’ disease. It should be taken into consideration that, in the early stages of thyroid-associated ophthalmopathy (TAO) in adults, only the superior oblique muscle may be enlarged.http://dx.doi.org/10.1155/2020/8829655
spellingShingle Keiichi Aomatsu
Shunji Kusaka
Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ Disease
Case Reports in Ophthalmological Medicine
title Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ Disease
title_full Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ Disease
title_fullStr Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ Disease
title_full_unstemmed Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ Disease
title_short Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves’ Disease
title_sort isolated superior oblique muscle swelling causing acute vertical strabismus in graves disease
url http://dx.doi.org/10.1155/2020/8829655
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AT shunjikusaka isolatedsuperiorobliquemuscleswellingcausingacuteverticalstrabismusingravesdisease