A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSI

Abstract Background A total of three techniques are used to guide tibial cuts in high tibial osteotomy (HTO): the conventional method, navigation systems, and patient-specific instrumentation (PSI). This network meta-analysis sought to assess whether any of these methods achieve better radiological...

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Main Authors: Fanny Delaigue, Hassan Wardani, Jules Descamps, Matthieu Ollivier, Rémy Nizard, Pierre-Alban Bouché
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Knee Surgery & Related Research
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Online Access:https://doi.org/10.1186/s43019-025-00278-1
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author Fanny Delaigue
Hassan Wardani
Jules Descamps
Matthieu Ollivier
Rémy Nizard
Pierre-Alban Bouché
author_facet Fanny Delaigue
Hassan Wardani
Jules Descamps
Matthieu Ollivier
Rémy Nizard
Pierre-Alban Bouché
author_sort Fanny Delaigue
collection DOAJ
description Abstract Background A total of three techniques are used to guide tibial cuts in high tibial osteotomy (HTO): the conventional method, navigation systems, and patient-specific instrumentation (PSI). This network meta-analysis sought to assess whether any of these methods achieve better radiological outcomes, greater functional gains, or a reduced rate of complications. Design We included all controlled and noncontrolled trials comparing at least two of the surgical techniques. Primary outcomes were rates of medial proximal tibial angle (MPTA) and posterior tibial slope (PTS) outliers. Secondary outcomes included the rate of hip-knee-ankle (HKA) angle outliers, joint range of motion, postoperative clinical scores, and complication rates. Results The analysis included 24 studies with 1817 patients and 1951 operated knees. PSI did not reduce the rate of MPTA outliers compared with conventional techniques (95% credible intervals, CI [0.09–56.84]) or navigation (95% CI [0.03–25.62]), and navigation did not reduce the rate compared with conventional methods (95% CI [0.84–9.17]). Navigation reduced the rate of PTS outliers compared with conventional techniques (95% CI [1.93–1.56.104]). No study investigating PTS outliers with PSI was identified or included. Both navigation and PSI reduced the rate of HKA angle outliers (95% CI [1.33–3.16] and [1.15–42.61], respectively). Aside from the rate of HKA angle outliers and the Lysholm score between 1 and 2 years postoperatively, no differences were observed for other outcomes. Conclusions Navigation and PSI allow for more precise achievement of the PTS and HKA angle values set by the surgeons but do not affect long-term knee function or complication rates. However, the cost and limited availability of these techniques should be considered, especially in the absence of additional functional benefits.
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spelling doaj-art-90bccc08dc5e4b3eb5f43f4aac941c1e2025-08-20T03:22:50ZengBMCKnee Surgery & Related Research2234-24512025-06-013711910.1186/s43019-025-00278-1A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSIFanny Delaigue0Hassan Wardani1Jules Descamps2Matthieu Ollivier3Rémy Nizard4Pierre-Alban Bouché5Orthopedic and Traumatology Surgery Department, Unité de Chirurgie Orthopédique et Traumatologique, Lariboisière HospitalOrthopedic and Traumatology Surgery Department, Unité de Chirurgie Orthopédique et Traumatologique, Lariboisière HospitalOrthopedic and Traumatology Surgery Department, Unité de Chirurgie Orthopédique et Traumatologique, Lariboisière HospitalInstitute for Locomotion, Aix-Marseille UniversityOrthopedic and Traumatology Surgery Department, Unité de Chirurgie Orthopédique et Traumatologique, Lariboisière HospitalOrthopedic and Traumatology Surgery Department, Unité de Chirurgie Orthopédique et Traumatologique, Lariboisière HospitalAbstract Background A total of three techniques are used to guide tibial cuts in high tibial osteotomy (HTO): the conventional method, navigation systems, and patient-specific instrumentation (PSI). This network meta-analysis sought to assess whether any of these methods achieve better radiological outcomes, greater functional gains, or a reduced rate of complications. Design We included all controlled and noncontrolled trials comparing at least two of the surgical techniques. Primary outcomes were rates of medial proximal tibial angle (MPTA) and posterior tibial slope (PTS) outliers. Secondary outcomes included the rate of hip-knee-ankle (HKA) angle outliers, joint range of motion, postoperative clinical scores, and complication rates. Results The analysis included 24 studies with 1817 patients and 1951 operated knees. PSI did not reduce the rate of MPTA outliers compared with conventional techniques (95% credible intervals, CI [0.09–56.84]) or navigation (95% CI [0.03–25.62]), and navigation did not reduce the rate compared with conventional methods (95% CI [0.84–9.17]). Navigation reduced the rate of PTS outliers compared with conventional techniques (95% CI [1.93–1.56.104]). No study investigating PTS outliers with PSI was identified or included. Both navigation and PSI reduced the rate of HKA angle outliers (95% CI [1.33–3.16] and [1.15–42.61], respectively). Aside from the rate of HKA angle outliers and the Lysholm score between 1 and 2 years postoperatively, no differences were observed for other outcomes. Conclusions Navigation and PSI allow for more precise achievement of the PTS and HKA angle values set by the surgeons but do not affect long-term knee function or complication rates. However, the cost and limited availability of these techniques should be considered, especially in the absence of additional functional benefits.https://doi.org/10.1186/s43019-025-00278-1OsteotomyGenu varumNetwork meta-analysisTibial valgus osteotomiesCutting guides
spellingShingle Fanny Delaigue
Hassan Wardani
Jules Descamps
Matthieu Ollivier
Rémy Nizard
Pierre-Alban Bouché
A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSI
Knee Surgery & Related Research
Osteotomy
Genu varum
Network meta-analysis
Tibial valgus osteotomies
Cutting guides
title A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSI
title_full A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSI
title_fullStr A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSI
title_full_unstemmed A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSI
title_short A network meta-analysis evaluating valgization high tibial osteotomy cutting guides: improving surgical precision through navigation and PSI
title_sort network meta analysis evaluating valgization high tibial osteotomy cutting guides improving surgical precision through navigation and psi
topic Osteotomy
Genu varum
Network meta-analysis
Tibial valgus osteotomies
Cutting guides
url https://doi.org/10.1186/s43019-025-00278-1
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