Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode
The fabrication and electrochemical evaluation of two PVC membrane-based Ion-Selective electrodes responsive for ramipril drug have been proposed. The sensitive membranes were prepared using ramipril-phosphomolibdate and ramipril-tetraphenylborate ion-pair complexes as electroactive sensing material...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | International Journal of Analytical Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/954083 |
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| author | Hassan Arida Mona Ahmed Abdallah Ali |
| author_facet | Hassan Arida Mona Ahmed Abdallah Ali |
| author_sort | Hassan Arida |
| collection | DOAJ |
| description | The fabrication and electrochemical evaluation of two PVC membrane-based Ion-Selective electrodes responsive for ramipril drug have been proposed. The sensitive membranes were prepared using ramipril-phosphomolibdate and ramipril-tetraphenylborate ion-pair complexes as electroactive sensing materials in plasticized PVC support. The electrodes based on these materials provide near-Nernestian response (sensitivity of 53±0.5–54±0.5 mV/concentration decade) covering the concentration range of 1.0×10-2–1.0×10-5 mol L−1 with a detection limit of 3.0×10-6–4.0×10-6 mol L−1. The suggested electrodes have been successfully used in the determination of ramipril drug in some pharmaceutical formulations using direct potentiometry with average recovery of >96% and mean standard deviation of <3% (n=5). |
| format | Article |
| id | doaj-art-90a4f3e5c8d24b15af6a09e9a6e390f7 |
| institution | Kabale University |
| issn | 1687-8760 1687-8779 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Analytical Chemistry |
| spelling | doaj-art-90a4f3e5c8d24b15af6a09e9a6e390f72025-02-03T01:23:39ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792009-01-01200910.1155/2009/954083954083Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective ElectrodeHassan Arida0Mona Ahmed1Abdallah Ali2Hot Laboratories Center, Atomic Energy Authority, Cairo 13759, EgyptGirls College, Ain Shams University, Cairo 11757, EgyptGirls College, Ain Shams University, Cairo 11757, EgyptThe fabrication and electrochemical evaluation of two PVC membrane-based Ion-Selective electrodes responsive for ramipril drug have been proposed. The sensitive membranes were prepared using ramipril-phosphomolibdate and ramipril-tetraphenylborate ion-pair complexes as electroactive sensing materials in plasticized PVC support. The electrodes based on these materials provide near-Nernestian response (sensitivity of 53±0.5–54±0.5 mV/concentration decade) covering the concentration range of 1.0×10-2–1.0×10-5 mol L−1 with a detection limit of 3.0×10-6–4.0×10-6 mol L−1. The suggested electrodes have been successfully used in the determination of ramipril drug in some pharmaceutical formulations using direct potentiometry with average recovery of >96% and mean standard deviation of <3% (n=5).http://dx.doi.org/10.1155/2009/954083 |
| spellingShingle | Hassan Arida Mona Ahmed Abdallah Ali Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode International Journal of Analytical Chemistry |
| title | Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode |
| title_full | Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode |
| title_fullStr | Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode |
| title_full_unstemmed | Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode |
| title_short | Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode |
| title_sort | preparation characterization and analytical application of ramipril membrane based ion selective electrode |
| url | http://dx.doi.org/10.1155/2009/954083 |
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