Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia

Psychogenic nonepileptic seizures (PNES) are nonepileptic events characterized by seizure-like manifestations without abnormal electrical activity in the brain. Our case report illustrates the diagnostic journey of a young female with a history of schizophrenia and childhood trauma who had an initia...

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Main Authors: Sikander Chohan, Ali Chohan, Muhamid Asif
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2023/6644876
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author Sikander Chohan
Ali Chohan
Muhamid Asif
author_facet Sikander Chohan
Ali Chohan
Muhamid Asif
author_sort Sikander Chohan
collection DOAJ
description Psychogenic nonepileptic seizures (PNES) are nonepileptic events characterized by seizure-like manifestations without abnormal electrical activity in the brain. Our case report illustrates the diagnostic journey of a young female with a history of schizophrenia and childhood trauma who had an initial misdiagnosis of epilepsy. The etiology of PNES is complex. Major depressive disorder and generalized anxiety disorder are common comorbid conditions in these patients. Additionally, previous trauma has been linked as a predisposing factor for the development of PNES. Psychotic disorders, specifically schizophrenia, have only recently been associated with PNES. We explore this relationship in depth, while also underscoring the diagnostic and treatment challenges of PNES that clinicians must remain aware of.
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series Case Reports in Psychiatry
spelling doaj-art-90a13770768d4cbeb07ef29819e05f342025-02-03T05:44:34ZengWileyCase Reports in Psychiatry2090-68382023-01-01202310.1155/2023/6644876Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and SchizophreniaSikander Chohan0Ali Chohan1Muhamid Asif2Wayne State University School of MedicineWestern Michigan University Homer Stryker M.D. School of MedicineProMedica Physicians Family Medicine FremontPsychogenic nonepileptic seizures (PNES) are nonepileptic events characterized by seizure-like manifestations without abnormal electrical activity in the brain. Our case report illustrates the diagnostic journey of a young female with a history of schizophrenia and childhood trauma who had an initial misdiagnosis of epilepsy. The etiology of PNES is complex. Major depressive disorder and generalized anxiety disorder are common comorbid conditions in these patients. Additionally, previous trauma has been linked as a predisposing factor for the development of PNES. Psychotic disorders, specifically schizophrenia, have only recently been associated with PNES. We explore this relationship in depth, while also underscoring the diagnostic and treatment challenges of PNES that clinicians must remain aware of.http://dx.doi.org/10.1155/2023/6644876
spellingShingle Sikander Chohan
Ali Chohan
Muhamid Asif
Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia
Case Reports in Psychiatry
title Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia
title_full Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia
title_fullStr Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia
title_full_unstemmed Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia
title_short Psychogenic Nonepileptic Seizures (PNES) in the Setting of Trauma and Schizophrenia
title_sort psychogenic nonepileptic seizures pnes in the setting of trauma and schizophrenia
url http://dx.doi.org/10.1155/2023/6644876
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