The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositis
Juvenile dermatomyositis (JDM) is the most common inflammatory myositis in children that primarily involves the skeletal muscles and skin. However, it can manifest with a diverse range of clinical features across multiple organ systems. JDM vasculopathy causing optic neuritis and medullary bone infa...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-01-01
|
| Series: | Indian Journal of Rheumatology |
| Subjects: | |
| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=3;spage=306;epage=310;aulast=Hegde |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849693177900957696 |
|---|---|
| author | Arun Hegde Suchi Acharya Subramanian Shankar Abhishek Kumar Uday Bhanu Kovilapu |
| author_facet | Arun Hegde Suchi Acharya Subramanian Shankar Abhishek Kumar Uday Bhanu Kovilapu |
| author_sort | Arun Hegde |
| collection | DOAJ |
| description | Juvenile dermatomyositis (JDM) is the most common inflammatory myositis in children that primarily involves the skeletal muscles and skin. However, it can manifest with a diverse range of clinical features across multiple organ systems. JDM vasculopathy causing optic neuritis and medullary bone infarcts in children are rare manifestations of JDM and have been seldom reported in literature. Similarly, cardiovascular manifestations in the form of refractory myocarditis leading to congestive cardiac failure during the early course of the disease have also been rare findings. Early diagnosis and aggressive management of such complications using biological disease-modifying synthetic antirheumatic drugs has significantly reduced the mortality and morbidity associated with JDM. Herein, we report a mini case series of three patients with JDM who presented with these rare systemic manifestations and achieved favorable outcomes while being managed using the Childhood Arthritis and Research Alliance-Treatment Protocols. |
| format | Article |
| id | doaj-art-908c52be4531489c8ebae2dba40f8eb7 |
| institution | DOAJ |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-908c52be4531489c8ebae2dba40f8eb72025-08-20T03:20:30ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012022-01-0117330631010.4103/injr.injr_51_21The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositisArun HegdeSuchi AcharyaSubramanian ShankarAbhishek KumarUday Bhanu KovilapuJuvenile dermatomyositis (JDM) is the most common inflammatory myositis in children that primarily involves the skeletal muscles and skin. However, it can manifest with a diverse range of clinical features across multiple organ systems. JDM vasculopathy causing optic neuritis and medullary bone infarcts in children are rare manifestations of JDM and have been seldom reported in literature. Similarly, cardiovascular manifestations in the form of refractory myocarditis leading to congestive cardiac failure during the early course of the disease have also been rare findings. Early diagnosis and aggressive management of such complications using biological disease-modifying synthetic antirheumatic drugs has significantly reduced the mortality and morbidity associated with JDM. Herein, we report a mini case series of three patients with JDM who presented with these rare systemic manifestations and achieved favorable outcomes while being managed using the Childhood Arthritis and Research Alliance-Treatment Protocols.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=3;spage=306;epage=310;aulast=Hegdebronchiolitis obliterans organizing pneumoniacalcinosischildhood arthritis rheumatology and research alliancejuvenile dermatomyositisrituximab |
| spellingShingle | Arun Hegde Suchi Acharya Subramanian Shankar Abhishek Kumar Uday Bhanu Kovilapu The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositis Indian Journal of Rheumatology bronchiolitis obliterans organizing pneumonia calcinosis childhood arthritis rheumatology and research alliance juvenile dermatomyositis rituximab |
| title | The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositis |
| title_full | The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositis |
| title_fullStr | The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositis |
| title_full_unstemmed | The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositis |
| title_short | The weeping heart, the choked lung, the blinded eye, and the crying femur: A saga of juvenile dermatomyositis |
| title_sort | weeping heart the choked lung the blinded eye and the crying femur a saga of juvenile dermatomyositis |
| topic | bronchiolitis obliterans organizing pneumonia calcinosis childhood arthritis rheumatology and research alliance juvenile dermatomyositis rituximab |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2022;volume=17;issue=3;spage=306;epage=310;aulast=Hegde |
| work_keys_str_mv | AT arunhegde theweepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT suchiacharya theweepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT subramanianshankar theweepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT abhishekkumar theweepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT udaybhanukovilapu theweepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT arunhegde weepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT suchiacharya weepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT subramanianshankar weepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT abhishekkumar weepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis AT udaybhanukovilapu weepingheartthechokedlungtheblindedeyeandthecryingfemurasagaofjuveniledermatomyositis |