Zafirlukast ameliorates lipopolysaccharide and bleomycin-induced lung inflammation in mice

Zafirlukast ameliorates lipopolysaccharide and bleomycin-induced lung inflammation in mice

Abstract Acute lung injury (ALI) is the result of damage to the capillary endothelia and the alveolar epithelial cell caused by various direct and indirect factors, leading to significant pulmonary interstitial and alveolar edema and acute hypoxic respiratory insufficiency. A subset of ALI cases pro...

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Main Authors: Tongtong Xue, Qianyi Zhang, Tiantian Zhang, Lingxin Meng, Jing Liu, Dan Chai, Yuming Liu, Zhongyi Yang, Ran Jiao, Yunyao Cui, Jingjing Gao, Xiaohe Li, Aiguo Xu, Honggang Zhou
Format: Article
Language:English
Published: BMC 2024-09-01
Series:BMC Pulmonary Medicine
Subjects:
Zafirlukast
Acute lung injury
Epithelial cell
NF-κB
Online Access:https://doi.org/10.1186/s12890-024-03273-6
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