High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network

IntroductionIn recent years, advancements in machine learning and electronic stethoscope technology have enabled high-precision recording and analysis of lung sounds, significantly enhancing pulmonary disease diagnosis.MethodsThis study presents a comprehensive approach to classify lung sounds into...

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Main Authors: Weiwei Zhang, Xinyu Li, Qiao Liu, Xiangyang Zheng, Yisu Ge, Xiaotian Pan, Yu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1583416/full
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author Weiwei Zhang
Xinyu Li
Qiao Liu
Xiangyang Zheng
Yisu Ge
Xiaotian Pan
Xiaotian Pan
Yu Zhou
author_facet Weiwei Zhang
Xinyu Li
Qiao Liu
Xiangyang Zheng
Yisu Ge
Xiaotian Pan
Xiaotian Pan
Yu Zhou
author_sort Weiwei Zhang
collection DOAJ
description IntroductionIn recent years, advancements in machine learning and electronic stethoscope technology have enabled high-precision recording and analysis of lung sounds, significantly enhancing pulmonary disease diagnosis.MethodsThis study presents a comprehensive approach to classify lung sounds into healthy and unhealthy categories using a dataset collected from 112 subjects, comprising 35 healthy individuals and 77 patients with various pulmonary conditions, such as asthma, heart failure, pneumonia, bronchitis, pleural effusion, lung fibrosis, and chronic obstructive pulmonary disease (COPD), grouped as unhealthy. The dataset was obtained using a 3M Littmann® Electronic Stethoscope Model 3,200, employing three types of filters (Bell, Diaphragm, and Extended) to capture sounds across different frequency ranges. We extracted five key audio features—Spectral Centroid, Power, Energy, Zero Crossing Rate, and Mel-Frequency Cepstral Coefficients (MFCCs)—from each recording to form a feature matrix. A Multi-Layer Perceptron (MLP) neural network was trained for binary classification.ResultsThe MLP neural network achieved accuracies of 98%, 100%, and 94% on the training, validation, and testing sets, respectively. This partitioning ensured the model’s robustness and accuracy.DiscussionThe high classification accuracy achieved by the MLP neural network suggests that this approach is a valuable decision-support tool for identifying healthy versus unhealthy lung sounds in clinical settings, facilitating early intervention while maintaining computational efficiency for offline implementation. The combination of detailed feature extraction and an optimized MLP neural network resulted in a reliable method for automated binary classification of lung sounds.
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spelling doaj-art-90858cb7f13944cd8452b3d2bdf715d12025-08-20T03:30:40ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-07-011310.3389/fbioe.2025.15834161583416High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural networkWeiwei Zhang0Xinyu Li1Qiao Liu2Xiangyang Zheng3Yisu Ge4Xiaotian Pan5Xiaotian Pan6Yu Zhou7Infectious Disease Department, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaChina Telecom Corporation Limited Zhejiang Branch, Hangzhou, ChinaInformation Technology Center, Wenzhou Medical University, Wenzhou, ChinaSchool of Data Science and Artificial Intelligence, Wenzhou University of Technology, Wenzhou, ChinaCollege of Computer Science and Artificial Intelligence, Wenzhou University, Wenzhou, ChinaInstitute of Intelligent Media Computing, Hangzhou Dianzi University, Hangzhou, ChinaShangyu Institute of Science and Engineering Co. Ltd., Hangzhou Dianzi University, Shaoxing, ChinaInfectious Disease Department, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, ChinaIntroductionIn recent years, advancements in machine learning and electronic stethoscope technology have enabled high-precision recording and analysis of lung sounds, significantly enhancing pulmonary disease diagnosis.MethodsThis study presents a comprehensive approach to classify lung sounds into healthy and unhealthy categories using a dataset collected from 112 subjects, comprising 35 healthy individuals and 77 patients with various pulmonary conditions, such as asthma, heart failure, pneumonia, bronchitis, pleural effusion, lung fibrosis, and chronic obstructive pulmonary disease (COPD), grouped as unhealthy. The dataset was obtained using a 3M Littmann® Electronic Stethoscope Model 3,200, employing three types of filters (Bell, Diaphragm, and Extended) to capture sounds across different frequency ranges. We extracted five key audio features—Spectral Centroid, Power, Energy, Zero Crossing Rate, and Mel-Frequency Cepstral Coefficients (MFCCs)—from each recording to form a feature matrix. A Multi-Layer Perceptron (MLP) neural network was trained for binary classification.ResultsThe MLP neural network achieved accuracies of 98%, 100%, and 94% on the training, validation, and testing sets, respectively. This partitioning ensured the model’s robustness and accuracy.DiscussionThe high classification accuracy achieved by the MLP neural network suggests that this approach is a valuable decision-support tool for identifying healthy versus unhealthy lung sounds in clinical settings, facilitating early intervention while maintaining computational efficiency for offline implementation. The combination of detailed feature extraction and an optimized MLP neural network resulted in a reliable method for automated binary classification of lung sounds.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1583416/fullmachine learningpulmonary disease classificationlung soundselectronic stethoscopemulti-layer perceptronfeature extraction
spellingShingle Weiwei Zhang
Xinyu Li
Qiao Liu
Xiangyang Zheng
Yisu Ge
Xiaotian Pan
Xiaotian Pan
Yu Zhou
High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network
Frontiers in Bioengineering and Biotechnology
machine learning
pulmonary disease classification
lung sounds
electronic stethoscope
multi-layer perceptron
feature extraction
title High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network
title_full High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network
title_fullStr High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network
title_full_unstemmed High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network
title_short High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network
title_sort high accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network
topic machine learning
pulmonary disease classification
lung sounds
electronic stethoscope
multi-layer perceptron
feature extraction
url https://www.frontiersin.org/articles/10.3389/fbioe.2025.1583416/full
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