Epigenetic aspects in rehabilitation of female cancer patients
The influence of epigenetic processes on the development of malignant diseases, including gynaecological cancers, is now beyond doubt. DNA methylation, histone modification and post-transcriptional regulation by microRNAs lead to changes in the activity of various genes, contributing to female genit...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2022-07-01
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| Series: | Фармакоэкономика |
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| Online Access: | https://www.pharmacoeconomics.ru/jour/article/view/701 |
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| _version_ | 1849394942577737728 |
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| author | A. G. Solopova D. V. Blinov S. V. Demyanov G. V. Demyanov E. E. Achkasov A. Yu. Vlasina L. N. Sandzhieva D. M. Ampilogova |
| author_facet | A. G. Solopova D. V. Blinov S. V. Demyanov G. V. Demyanov E. E. Achkasov A. Yu. Vlasina L. N. Sandzhieva D. M. Ampilogova |
| author_sort | A. G. Solopova |
| collection | DOAJ |
| description | The influence of epigenetic processes on the development of malignant diseases, including gynaecological cancers, is now beyond doubt. DNA methylation, histone modification and post-transcriptional regulation by microRNAs lead to changes in the activity of various genes, contributing to female genital cancers (cervix, endometrium, ovarian). It should be noted that disruptions in gene expression do not only occur in malignant cells, but also in the tumour microenvironment, resulting in disease progression and relapse. However, “epigenetic markers” of carcinogenesis can be useful in the treatment and rehabilitation of patients, making a personalized approach possible. |
| format | Article |
| id | doaj-art-90851f14a8364ceca75d2317762cffbb |
| institution | Kabale University |
| issn | 2070-4909 2070-4933 |
| language | Russian |
| publishDate | 2022-07-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Фармакоэкономика |
| spelling | doaj-art-90851f14a8364ceca75d2317762cffbb2025-08-20T03:39:49ZrusIRBIS LLCФармакоэкономика2070-49092070-49332022-07-0115229430310.17749/2070-4909/farmakoekonomika.2022.141399Epigenetic aspects in rehabilitation of female cancer patientsA. G. Solopova0D. V. Blinov1S. V. Demyanov2G. V. Demyanov3E. E. Achkasov4A. Yu. Vlasina5L. N. Sandzhieva6D. M. Ampilogova7Sechenov UniversityInstitute for Preventive and Social Medicine; Lapino Clinical Hospital, Medical Group “Mother and Child”; Moscow Haass Medical Social InstituteSechenov UniversitySechenov UniversitySechenov UniversitySechenov UniversitySechenov UniversitySechenov UniversityThe influence of epigenetic processes on the development of malignant diseases, including gynaecological cancers, is now beyond doubt. DNA methylation, histone modification and post-transcriptional regulation by microRNAs lead to changes in the activity of various genes, contributing to female genital cancers (cervix, endometrium, ovarian). It should be noted that disruptions in gene expression do not only occur in malignant cells, but also in the tumour microenvironment, resulting in disease progression and relapse. However, “epigenetic markers” of carcinogenesis can be useful in the treatment and rehabilitation of patients, making a personalized approach possible.https://www.pharmacoeconomics.ru/jour/article/view/701epigeneticsgynaecological oncologytumour microenvironmentrehabilitationtumour markers |
| spellingShingle | A. G. Solopova D. V. Blinov S. V. Demyanov G. V. Demyanov E. E. Achkasov A. Yu. Vlasina L. N. Sandzhieva D. M. Ampilogova Epigenetic aspects in rehabilitation of female cancer patients Фармакоэкономика epigenetics gynaecological oncology tumour microenvironment rehabilitation tumour markers |
| title | Epigenetic aspects in rehabilitation of female cancer patients |
| title_full | Epigenetic aspects in rehabilitation of female cancer patients |
| title_fullStr | Epigenetic aspects in rehabilitation of female cancer patients |
| title_full_unstemmed | Epigenetic aspects in rehabilitation of female cancer patients |
| title_short | Epigenetic aspects in rehabilitation of female cancer patients |
| title_sort | epigenetic aspects in rehabilitation of female cancer patients |
| topic | epigenetics gynaecological oncology tumour microenvironment rehabilitation tumour markers |
| url | https://www.pharmacoeconomics.ru/jour/article/view/701 |
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