Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report
Azoospermia, the absence of sperm in the ejaculate, affects 1 % of men, with non-obstructive azoospermia (NOA) comprising 60 % of cases. We report a 29-year-old male with NOA and primary infertility, initially asymptomatic with history of chronic diseases and normal evaluations. Routine blood tests...
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| Language: | English |
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Elsevier
2025-05-01
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| Series: | Urology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442025001123 |
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| author | Raneen Sawaid Kaiyal Hala Aslih Inshirah Sgayer Lior Lowenstein Ekaterina Shlush |
| author_facet | Raneen Sawaid Kaiyal Hala Aslih Inshirah Sgayer Lior Lowenstein Ekaterina Shlush |
| author_sort | Raneen Sawaid Kaiyal |
| collection | DOAJ |
| description | Azoospermia, the absence of sperm in the ejaculate, affects 1 % of men, with non-obstructive azoospermia (NOA) comprising 60 % of cases. We report a 29-year-old male with NOA and primary infertility, initially asymptomatic with history of chronic diseases and normal evaluations. Routine blood tests revealed elevated creatinine, leading to a diagnosis of end-stage renal disease (ESRD) due to focal segmental glomerulosclerosis. After hemodialysis and kidney transplantation, semen analysis showed cryptozoospermia, suggesting partial spermatogenesis recovery. This case highlights NOA as a potential silent indicator of systemic disease, emphasizing the importance of thorough evaluation and a multidisciplinary approach in idiopathic cases. |
| format | Article |
| id | doaj-art-9082a08576034497abaaba8f0e02c9d7 |
| institution | OA Journals |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-9082a08576034497abaaba8f0e02c9d72025-08-20T02:24:38ZengElsevierUrology Case Reports2214-44202025-05-016010304110.1016/j.eucr.2025.103041Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case reportRaneen Sawaid Kaiyal0Hala Aslih1Inshirah Sgayer2Lior Lowenstein3Ekaterina Shlush4Department of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, Israel; Corresponding author. Department of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, 2210001, Israel.Department of Obstetrics and Gynecology, Nazareth Hospital EMMS, Nazareth, IsraelDepartment of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, Israel; Azrieli Faculty of Medicine, Bar Ilan University, Safed, IsraelDepartment of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, Israel; Azrieli Faculty of Medicine, Bar Ilan University, Safed, IsraelDepartment of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, IsraelAzoospermia, the absence of sperm in the ejaculate, affects 1 % of men, with non-obstructive azoospermia (NOA) comprising 60 % of cases. We report a 29-year-old male with NOA and primary infertility, initially asymptomatic with history of chronic diseases and normal evaluations. Routine blood tests revealed elevated creatinine, leading to a diagnosis of end-stage renal disease (ESRD) due to focal segmental glomerulosclerosis. After hemodialysis and kidney transplantation, semen analysis showed cryptozoospermia, suggesting partial spermatogenesis recovery. This case highlights NOA as a potential silent indicator of systemic disease, emphasizing the importance of thorough evaluation and a multidisciplinary approach in idiopathic cases.http://www.sciencedirect.com/science/article/pii/S2214442025001123Male infertilityAzoospermiaChronic kidney diseaseEnd-stage kidney failureTransplantHypogonadism |
| spellingShingle | Raneen Sawaid Kaiyal Hala Aslih Inshirah Sgayer Lior Lowenstein Ekaterina Shlush Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report Urology Case Reports Male infertility Azoospermia Chronic kidney disease End-stage kidney failure Transplant Hypogonadism |
| title | Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report |
| title_full | Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report |
| title_fullStr | Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report |
| title_full_unstemmed | Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report |
| title_short | Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report |
| title_sort | non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure a case report |
| topic | Male infertility Azoospermia Chronic kidney disease End-stage kidney failure Transplant Hypogonadism |
| url | http://www.sciencedirect.com/science/article/pii/S2214442025001123 |
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