Hepatitis C virus translation preferentially depends on active RNA replication.

Hepatitis C virus translation preferentially depends on active RNA replication.

Hepatitis C virus (HCV) RNA initiates its replication on a detergent-resistant membrane structure derived from the endoplasmic reticulum (ER) in the HCV replicon cells. By performing a pulse-chase study of BrU-labeled HCV RNA, we found that the newly-synthesized HCV RNA traveled along the anterograd...

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Bibliographic Details
Main Authors: Helene Minyi Liu, Hideki Aizaki, Keigo Machida, J-H James Ou, Michael M C Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043600&type=printable
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