Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes

Nanomaterial advancements have heralded a new era in electrochemical sensing by enabling the precise modification of boron-doped diamond (BDD) electrodes. This review investigates recent remarkable advances, challenges, and potential future directions of nanomaterial-modified BDD electrodes for bios...

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Main Authors: Pramod K. Gupta, James R. Siegenthaler
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Chemosensors
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Online Access:https://www.mdpi.com/2227-9040/13/5/183
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author Pramod K. Gupta
James R. Siegenthaler
author_facet Pramod K. Gupta
James R. Siegenthaler
author_sort Pramod K. Gupta
collection DOAJ
description Nanomaterial advancements have heralded a new era in electrochemical sensing by enabling the precise modification of boron-doped diamond (BDD) electrodes. This review investigates recent remarkable advances, challenges, and potential future directions of nanomaterial-modified BDD electrodes for biosensing applications, emphasizing their game-changing potential. This review begins by investigating the intrinsic properties of boron-doped diamond electrodes, emphasizing their inherent advantages in electrochemical biosensing. Following that, it embarks on an illuminating journey through the spectrum of nanomaterials that have revolutionized these electrodes. These materials include carbon-based nanomaterials, metal and metal oxide nanostructures, their combinations, patterned nanostructures on BDDs, and other nanomaterials, each with unique properties that can be used to tailor BDD electrodes to specific applications. Throughout this article, we explain how these nanomaterials improve BDD electrodes, from accelerated electron transfer kinetics to increased surface area and sensitivity, promising unprecedented performance. Beyond experimentation, it investigates the challenges—stability, reproducibility, and scalability—associated with the use of nanomaterials in BDD electrode modifications, as well as the ecological and economic implications. Furthermore, the future prospects of nanomaterial-modified BDD electrodes hold the key to addressing pressing contemporary research challenges.
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spelling doaj-art-906672bd685b4d869c7c8d4ab494a6e22025-08-20T03:14:31ZengMDPI AGChemosensors2227-90402025-05-0113518310.3390/chemosensors13050183Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond ElectrodesPramod K. Gupta0James R. Siegenthaler1Coatings and Diamond Technologies, Fraunhofer USA CMW, East Lansing, MI 48824, USACoatings and Diamond Technologies, Fraunhofer USA CMW, East Lansing, MI 48824, USANanomaterial advancements have heralded a new era in electrochemical sensing by enabling the precise modification of boron-doped diamond (BDD) electrodes. This review investigates recent remarkable advances, challenges, and potential future directions of nanomaterial-modified BDD electrodes for biosensing applications, emphasizing their game-changing potential. This review begins by investigating the intrinsic properties of boron-doped diamond electrodes, emphasizing their inherent advantages in electrochemical biosensing. Following that, it embarks on an illuminating journey through the spectrum of nanomaterials that have revolutionized these electrodes. These materials include carbon-based nanomaterials, metal and metal oxide nanostructures, their combinations, patterned nanostructures on BDDs, and other nanomaterials, each with unique properties that can be used to tailor BDD electrodes to specific applications. Throughout this article, we explain how these nanomaterials improve BDD electrodes, from accelerated electron transfer kinetics to increased surface area and sensitivity, promising unprecedented performance. Beyond experimentation, it investigates the challenges—stability, reproducibility, and scalability—associated with the use of nanomaterials in BDD electrode modifications, as well as the ecological and economic implications. Furthermore, the future prospects of nanomaterial-modified BDD electrodes hold the key to addressing pressing contemporary research challenges.https://www.mdpi.com/2227-9040/13/5/183boron-doped diamondnanomaterialselectrochemistryelectrode modificationbiosensing
spellingShingle Pramod K. Gupta
James R. Siegenthaler
Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes
Chemosensors
boron-doped diamond
nanomaterials
electrochemistry
electrode modification
biosensing
title Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes
title_full Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes
title_fullStr Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes
title_full_unstemmed Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes
title_short Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes
title_sort revolutionizing electrochemical sensing with nanomaterial modified boron doped diamond electrodes
topic boron-doped diamond
nanomaterials
electrochemistry
electrode modification
biosensing
url https://www.mdpi.com/2227-9040/13/5/183
work_keys_str_mv AT pramodkgupta revolutionizingelectrochemicalsensingwithnanomaterialmodifiedborondopeddiamondelectrodes
AT jamesrsiegenthaler revolutionizingelectrochemicalsensingwithnanomaterialmodifiedborondopeddiamondelectrodes