Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis

Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved...

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Main Authors: Peng Peng, Xiuyuan Liu, Lin Yang, Zhenguang Gu, Lin Cai
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Genetics Research
Online Access:http://dx.doi.org/10.1155/2023/9923428
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author Peng Peng
Xiuyuan Liu
Lin Yang
Zhenguang Gu
Lin Cai
author_facet Peng Peng
Xiuyuan Liu
Lin Yang
Zhenguang Gu
Lin Cai
author_sort Peng Peng
collection DOAJ
description Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved the information of 780 GCOM cases from the Surveillance, Epidemiology, and End Results (SEERs) database and analyzed their clinicopathological characteristics as well as their survival. According to our data, most GCOM patients showed poor pathological differentiation, advanced T and N stages. The prognostic factors include patients’ age, tumor size, surgical resection, and chemotherapy treatment. Of note, the marriage status was also identified as an independent prognostic factor. Besides the identification of prognostic factors, we established nomograms to help predict the overall survival and cancer-specific survival of GCOM, respectively.
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issn 1469-5073
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series Genetics Research
spelling doaj-art-9064601f728846a4bd73676a41f30fe42025-08-20T03:18:56ZengWileyGenetics Research1469-50732023-01-01202310.1155/2023/9923428Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian MetastasisPeng Peng0Xiuyuan Liu1Lin Yang2Zhenguang Gu3Lin Cai4Department of General SurgeryDepartment of General SurgeryDepartment of General SurgeryDepartment of General SurgerySchool of Food and DrugOvarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved the information of 780 GCOM cases from the Surveillance, Epidemiology, and End Results (SEERs) database and analyzed their clinicopathological characteristics as well as their survival. According to our data, most GCOM patients showed poor pathological differentiation, advanced T and N stages. The prognostic factors include patients’ age, tumor size, surgical resection, and chemotherapy treatment. Of note, the marriage status was also identified as an independent prognostic factor. Besides the identification of prognostic factors, we established nomograms to help predict the overall survival and cancer-specific survival of GCOM, respectively.http://dx.doi.org/10.1155/2023/9923428
spellingShingle Peng Peng
Xiuyuan Liu
Lin Yang
Zhenguang Gu
Lin Cai
Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
Genetics Research
title Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_full Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_fullStr Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_full_unstemmed Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_short Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_sort systematically prognostic analyses of gastric cancer patients with ovarian metastasis
url http://dx.doi.org/10.1155/2023/9923428
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AT xiuyuanliu systematicallyprognosticanalysesofgastriccancerpatientswithovarianmetastasis
AT linyang systematicallyprognosticanalysesofgastriccancerpatientswithovarianmetastasis
AT zhenguanggu systematicallyprognosticanalysesofgastriccancerpatientswithovarianmetastasis
AT lincai systematicallyprognosticanalysesofgastriccancerpatientswithovarianmetastasis