Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, Ethiopia
Caseous lymphadenitis (CLA) is a bacterial disease of small ruminants causing abscesses in lymph nodes of the body and internal organs. A longitudinal study from 2011 to 2019 was undertaken at Ataye site of Debre Birhan Research Center to estimate the prevalence and incidence, identify associated ri...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Veterinary Medicine International |
| Online Access: | http://dx.doi.org/10.1155/2020/8822997 |
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| author | Erdachew Yitagesu Enyiew Alemnew Abebe Olani Tadiwos Asfaw Chekol Demis |
| author_facet | Erdachew Yitagesu Enyiew Alemnew Abebe Olani Tadiwos Asfaw Chekol Demis |
| author_sort | Erdachew Yitagesu |
| collection | DOAJ |
| description | Caseous lymphadenitis (CLA) is a bacterial disease of small ruminants causing abscesses in lymph nodes of the body and internal organs. A longitudinal study from 2011 to 2019 was undertaken at Ataye site of Debre Birhan Research Center to estimate the prevalence and incidence, identify associated risk factors, and characterize the causative bacteria. 1025 goats were followed up for the CLA study. Survival analysis was done using SAS 9.4 software program. Biochemical tests and Biolog microbial identification system were used to characterize the bacteria. In the recurrent survival data analysis, there were 1,138 clinical observations and 214 CLA cases (18.8% prevalence) based on clinical diagnosis. The incidence rate was 0.14 cases per animal year. From a total of 214 cases, 130 have occurred once and 84 cases are recurrent cases following first cases. The cumulative failure rates were 68% for newborn and 64% for yearling age groups. The parotid lymph node was the most frequently affected site. Proportional hazard analysis results showed that sex, age, and breed were associated (p<0.05) with CLA incidence. Females, newborn age group, Boer, and Boer × Central Highland Goat (CHG) were at higher risks compared to males, yearling age group, and CHG goats, respectively. The present study indicated that a high incidence rate of CLA in the goat farm is difficult to control and prevent because of its poor response to clinical treatment. Thus, control and prevention should focus on the spread of the disease such as isolation of clinically sick animals, culling, and vaccination of flocks. |
| format | Article |
| id | doaj-art-9059d06a991e4c7ca87be63e414dded6 |
| institution | OA Journals |
| issn | 2090-8113 2042-0048 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
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| series | Veterinary Medicine International |
| spelling | doaj-art-9059d06a991e4c7ca87be63e414dded62025-08-20T02:09:14ZengWileyVeterinary Medicine International2090-81132042-00482020-01-01202010.1155/2020/88229978822997Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, EthiopiaErdachew Yitagesu0Enyiew Alemnew1Abebe Olani2Tadiwos Asfaw3Chekol Demis4Debre Birhan Agricultural Research Center, P.O. Box 112, Debre Birhan, EthiopiaDebre Birhan Agricultural Research Center, P.O. Box 112, Debre Birhan, EthiopiaDepartment of Parasitology, National Animal Health Diagnostic and Investigation Center (NAHDIC), P.O. Box 04, Sebeta, EthiopiaDebre Birhan Agricultural Research Center, P.O. Box 112, Debre Birhan, EthiopiaDebre Birhan Agricultural Research Center, P.O. Box 112, Debre Birhan, EthiopiaCaseous lymphadenitis (CLA) is a bacterial disease of small ruminants causing abscesses in lymph nodes of the body and internal organs. A longitudinal study from 2011 to 2019 was undertaken at Ataye site of Debre Birhan Research Center to estimate the prevalence and incidence, identify associated risk factors, and characterize the causative bacteria. 1025 goats were followed up for the CLA study. Survival analysis was done using SAS 9.4 software program. Biochemical tests and Biolog microbial identification system were used to characterize the bacteria. In the recurrent survival data analysis, there were 1,138 clinical observations and 214 CLA cases (18.8% prevalence) based on clinical diagnosis. The incidence rate was 0.14 cases per animal year. From a total of 214 cases, 130 have occurred once and 84 cases are recurrent cases following first cases. The cumulative failure rates were 68% for newborn and 64% for yearling age groups. The parotid lymph node was the most frequently affected site. Proportional hazard analysis results showed that sex, age, and breed were associated (p<0.05) with CLA incidence. Females, newborn age group, Boer, and Boer × Central Highland Goat (CHG) were at higher risks compared to males, yearling age group, and CHG goats, respectively. The present study indicated that a high incidence rate of CLA in the goat farm is difficult to control and prevent because of its poor response to clinical treatment. Thus, control and prevention should focus on the spread of the disease such as isolation of clinically sick animals, culling, and vaccination of flocks.http://dx.doi.org/10.1155/2020/8822997 |
| spellingShingle | Erdachew Yitagesu Enyiew Alemnew Abebe Olani Tadiwos Asfaw Chekol Demis Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, Ethiopia Veterinary Medicine International |
| title | Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, Ethiopia |
| title_full | Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, Ethiopia |
| title_fullStr | Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, Ethiopia |
| title_full_unstemmed | Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, Ethiopia |
| title_short | Survival Analysis of Clinical Cases of Caseous Lymphadenitis of Goats in North Shoa, Ethiopia |
| title_sort | survival analysis of clinical cases of caseous lymphadenitis of goats in north shoa ethiopia |
| url | http://dx.doi.org/10.1155/2020/8822997 |
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