Hepatoprotective activity of Alstonia boonei (De Wild) stem bark in isoniazid-induced Wistar rats: Antioxidant, anti-inflammatory and in silico evaluations

Hepatoprotective activity of Alstonia boonei (De Wild) stem bark in isoniazid-induced Wistar rats: Antioxidant, anti-inflammatory and in silico evaluations

Introduction: Liver damage is mainly caused by exposure to toxic chemicals and is a global health challenge. A variety of Alstonia species including Alstonia boonei has been used in Traditional Chinese Medicines (TCM) for the treatment of fever, asthma and as analgesics. In this research, the potent...

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Bibliographic Details
Main Authors: Adedotun F. Adesina, Joseph T. Apata, Olusegun O. Babalola, Chiagoziem A. Otuechere, Mukaila B. Adekola, Gbenga S. Ogunleye, Funke Asaolu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Isoniazid
Alstonia boonei stem bark
Hepatotoxicity
Antioxidant
Anti-Inflammatory
In silico
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142524002008
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