The Role of γδ T Cells in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the overproduction of autoantibodies against an array of nuclear and cytoplasmic antigens and affects multiple organs, such as the skin, joints, kidneys, and neuronal tissues. T cells have been recognized as importa...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2016/2932531 |
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| _version_ | 1850212888047779840 |
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| author | Meng Wu Jinhua Yang Xiaofeng Li Junwei Chen |
| author_facet | Meng Wu Jinhua Yang Xiaofeng Li Junwei Chen |
| author_sort | Meng Wu |
| collection | DOAJ |
| description | Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the overproduction of autoantibodies against an array of nuclear and cytoplasmic antigens and affects multiple organs, such as the skin, joints, kidneys, and neuronal tissues. T cells have been recognized as important players in the development of SLE due to their functions in cytokine secretion, antigen presentation, and supporting B cells for antibody production. γδ T cells are a minor population of T cells that play important roles in infection and tumor-associated disease. In recent years, the role of γδ T cells in autoimmune diseases has been investigated. In this review, we discussed the role of γδ T cells in the pathogenesis of SLE. |
| format | Article |
| id | doaj-art-9055d6287c5c4436870ae798ac1b3ecb |
| institution | OA Journals |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-9055d6287c5c4436870ae798ac1b3ecb2025-08-20T02:09:14ZengWileyJournal of Immunology Research2314-88612314-71562016-01-01201610.1155/2016/29325312932531The Role of γδ T Cells in Systemic Lupus ErythematosusMeng Wu0Jinhua Yang1Xiaofeng Li2Junwei Chen3Department of Rheumatology, The Second Hospital of Shanxi Medical University, Shanxi, Taiyuan 030001, ChinaDepartment of Rheumatology, The Second Hospital of Shanxi Medical University, Shanxi, Taiyuan 030001, ChinaDepartment of Rheumatology, The Second Hospital of Shanxi Medical University, Shanxi, Taiyuan 030001, ChinaDepartment of Rheumatology, The Second Hospital of Shanxi Medical University, Shanxi, Taiyuan 030001, ChinaSystemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the overproduction of autoantibodies against an array of nuclear and cytoplasmic antigens and affects multiple organs, such as the skin, joints, kidneys, and neuronal tissues. T cells have been recognized as important players in the development of SLE due to their functions in cytokine secretion, antigen presentation, and supporting B cells for antibody production. γδ T cells are a minor population of T cells that play important roles in infection and tumor-associated disease. In recent years, the role of γδ T cells in autoimmune diseases has been investigated. In this review, we discussed the role of γδ T cells in the pathogenesis of SLE.http://dx.doi.org/10.1155/2016/2932531 |
| spellingShingle | Meng Wu Jinhua Yang Xiaofeng Li Junwei Chen The Role of γδ T Cells in Systemic Lupus Erythematosus Journal of Immunology Research |
| title | The Role of γδ T Cells in Systemic Lupus Erythematosus |
| title_full | The Role of γδ T Cells in Systemic Lupus Erythematosus |
| title_fullStr | The Role of γδ T Cells in Systemic Lupus Erythematosus |
| title_full_unstemmed | The Role of γδ T Cells in Systemic Lupus Erythematosus |
| title_short | The Role of γδ T Cells in Systemic Lupus Erythematosus |
| title_sort | role of γδ t cells in systemic lupus erythematosus |
| url | http://dx.doi.org/10.1155/2016/2932531 |
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