Mucosal immunization with the lung Lactobacillus-derived amphiphilic exopolysaccharide adjuvanted recombinant vaccine improved protection against P. aeruginosa infection.
Respiratory infections caused by Pseudomonas aeruginosa are a major health problem globally. Current treatment for P. aeruginosa infections relies solely on antibiotics, but the rise of antibiotic-resistant strains necessitates an urgent need for a protective vaccine. Traditional parenteral vaccines...
Saved in:
| Main Authors: | Haochi Zhang, Shouxin Sheng, Chunhe Li, Xuemei Bao, Lixia Zhao, Jian Chen, Pingyuan Guan, Xiaoyan Li, Na Pan, Yanchen Liang, Xueqi Wang, Jingmin Sun, Xiao Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-11-01
|
| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1012696 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Spontaneous mutation reveals influence of exopolysaccharide on Lactobacillus johnsonii surface characteristics.
by: Nikki Horn, et al.
Published: (2013-01-01) -
Characterisation and bioactivity of an exopolysaccharide isolated from Lactobacillus rhamnosus LRH30 cultivations
by: Helena Mylise Copeland, et al.
Published: (2025-06-01) -
A biofilm-tropic Pseudomonas aeruginosa bacteriophage uses the exopolysaccharide Psl as receptor
by: Brenna Walton, et al.
Published: (2025-08-01) -
Assembly and the gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa
by: Marius Benedens, et al.
Published: (2025-06-01) -
Screening For Potential Exopolysaccharide Producers From Lactobacillus spp Isolated From Locally Fermented Milk (Nono)
by: Kabir, A., et al.
Published: (2022-06-01)