The Relationship Between Gut Microbiota and Recurrent Spontaneous Abortion
Recently, the gut microbiota has been found to be associated with multiple organs and systems in the human body, playing a key role in the occurrence and development of various diseases, such as the gut–brain axis and the gut–liver axis. However, its interaction with miscarriages remains poorly unde...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/13/5/1073 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849711001839075328 |
|---|---|
| author | Yiyao Huang Ruijie Fang Ting Xiong Wei Li Nan Yu |
| author_facet | Yiyao Huang Ruijie Fang Ting Xiong Wei Li Nan Yu |
| author_sort | Yiyao Huang |
| collection | DOAJ |
| description | Recently, the gut microbiota has been found to be associated with multiple organs and systems in the human body, playing a key role in the occurrence and development of various diseases, such as the gut–brain axis and the gut–liver axis. However, its interaction with miscarriages remains poorly understood. This article reviews the characteristics of gut microbiota and its metabolites in patients with recurrent spontaneous abortion (RSA), the mechanism of gut microbiota inducing RSA, and potential therapeutic strategies. Therefore, it provides a new perspective on the gut microbiota in the pathogenesis and treatment of recurrent abortion, and the prospect of the future research direction of gut microbiota and recurrent abortion is proposed based on existing studies. |
| format | Article |
| id | doaj-art-90468b8e14e94f628c4e64ee70826e7e |
| institution | DOAJ |
| issn | 2076-2607 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj-art-90468b8e14e94f628c4e64ee70826e7e2025-08-20T03:14:43ZengMDPI AGMicroorganisms2076-26072025-05-01135107310.3390/microorganisms13051073The Relationship Between Gut Microbiota and Recurrent Spontaneous AbortionYiyao Huang0Ruijie Fang1Ting Xiong2Wei Li3Nan Yu4Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, ChinaTongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, ChinaDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, ChinaDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, ChinaDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, ChinaRecently, the gut microbiota has been found to be associated with multiple organs and systems in the human body, playing a key role in the occurrence and development of various diseases, such as the gut–brain axis and the gut–liver axis. However, its interaction with miscarriages remains poorly understood. This article reviews the characteristics of gut microbiota and its metabolites in patients with recurrent spontaneous abortion (RSA), the mechanism of gut microbiota inducing RSA, and potential therapeutic strategies. Therefore, it provides a new perspective on the gut microbiota in the pathogenesis and treatment of recurrent abortion, and the prospect of the future research direction of gut microbiota and recurrent abortion is proposed based on existing studies.https://www.mdpi.com/2076-2607/13/5/1073recurrent spontaneous abortion (RSA)recurrent miscarriagesgut microbiotaimmunology |
| spellingShingle | Yiyao Huang Ruijie Fang Ting Xiong Wei Li Nan Yu The Relationship Between Gut Microbiota and Recurrent Spontaneous Abortion Microorganisms recurrent spontaneous abortion (RSA) recurrent miscarriages gut microbiota immunology |
| title | The Relationship Between Gut Microbiota and Recurrent Spontaneous Abortion |
| title_full | The Relationship Between Gut Microbiota and Recurrent Spontaneous Abortion |
| title_fullStr | The Relationship Between Gut Microbiota and Recurrent Spontaneous Abortion |
| title_full_unstemmed | The Relationship Between Gut Microbiota and Recurrent Spontaneous Abortion |
| title_short | The Relationship Between Gut Microbiota and Recurrent Spontaneous Abortion |
| title_sort | relationship between gut microbiota and recurrent spontaneous abortion |
| topic | recurrent spontaneous abortion (RSA) recurrent miscarriages gut microbiota immunology |
| url | https://www.mdpi.com/2076-2607/13/5/1073 |
| work_keys_str_mv | AT yiyaohuang therelationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT ruijiefang therelationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT tingxiong therelationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT weili therelationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT nanyu therelationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT yiyaohuang relationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT ruijiefang relationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT tingxiong relationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT weili relationshipbetweengutmicrobiotaandrecurrentspontaneousabortion AT nanyu relationshipbetweengutmicrobiotaandrecurrentspontaneousabortion |