Autoimmune disease: genetic susceptibility, environmental triggers, and immune dysregulation. Where can we develop therapies?

Autoimmune diseases are a diverse group of chronic disorders characterized by inappropriate immune responses against self-antigens, resulting in persistent inflammation and tissue destruction. Affecting an estimated 7–10% of the global population, these conditions include both systemic and organ-spe...

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Bibliographic Details
Main Authors: Manoj Kumar, Linda Yip, Fangyuan Wang, Saci-Elodie Marty, C. Garrison Fathman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1626082/full
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