Frequent PD-L1 expression in oral squamous cell carcinoma of non-smokers and non-drinkers, and association of tumor infiltrating lymphocytes with favorable prognosis.

Frequent PD-L1 expression in oral squamous cell carcinoma of non-smokers and non-drinkers, and association of tumor infiltrating lymphocytes with favorable prognosis.

Objectives: To determine the presence and prognostic value of PD-L1 and PD-L2 expression, and tumor-infiltrating lymphocytes (TILs) in oral squamous cell carcinoma (OSCC) of non-smokers and non-drinkers (NSND). Materials and methods: Clinical characteristics and tumor tissue of 86 NSND with OSCC wer...

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Bibliographic Details
Main Authors: FJ Mulder, EJ de Ruiter, TFB Gielgens, F Farshadpour, R de Bree, MFCM van den Hout, B Kremer, SM Willems, EJM Speel
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Translational Oncology
Subjects:
Head and neck cancer
Programmed death ligand 1
Tumor infiltrating lymphocytes
Non-smokers
Non-drinkers
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325000889
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