Epithelial reticular cells of the thymus and the regulatory T-lymphocytes

The article presents a review of the literature. The article presents the published data on the role of reticular epithelial cells in the formation of specific microenvironment in the cortex and medulla of thymic lobules. Thymic microenvironment plays a key role in T-cell differentiation. Discusses...

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Main Authors: V. E. Torbek, S. L. Kuznetsov
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2015-03-01
Series:Сеченовский вестник
Subjects:
Online Access:https://www.sechenovmedj.com/jour/article/view/681
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author V. E. Torbek
S. L. Kuznetsov
author_facet V. E. Torbek
S. L. Kuznetsov
author_sort V. E. Torbek
collection DOAJ
description The article presents a review of the literature. The article presents the published data on the role of reticular epithelial cells in the formation of specific microenvironment in the cortex and medulla of thymic lobules. Thymic microenvironment plays a key role in T-cell differentiation. Discusses the role of medullar epithelial cells in the development of regulatory T-lymphocytes and induction of tolerance.
format Article
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institution Kabale University
issn 2218-7332
2658-3348
language Russian
publishDate 2015-03-01
publisher Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
record_format Article
series Сеченовский вестник
spelling doaj-art-902a88280df24a3b962c06eccbd2ccfc2025-08-20T03:59:03ZrusFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Сеченовский вестник2218-73322658-33482015-03-01014549375Epithelial reticular cells of the thymus and the regulatory T-lymphocytesV. E. Torbek0S. L. Kuznetsov1I.M. Sechenov First MSMUI.M. Sechenov First MSMUThe article presents a review of the literature. The article presents the published data on the role of reticular epithelial cells in the formation of specific microenvironment in the cortex and medulla of thymic lobules. Thymic microenvironment plays a key role in T-cell differentiation. Discusses the role of medullar epithelial cells in the development of regulatory T-lymphocytes and induction of tolerance.https://www.sechenovmedj.com/jour/article/view/681thymusreticular epithelial cellsregulatory t-cellstolerance
spellingShingle V. E. Torbek
S. L. Kuznetsov
Epithelial reticular cells of the thymus and the regulatory T-lymphocytes
Сеченовский вестник
thymus
reticular epithelial cells
regulatory t-cells
tolerance
title Epithelial reticular cells of the thymus and the regulatory T-lymphocytes
title_full Epithelial reticular cells of the thymus and the regulatory T-lymphocytes
title_fullStr Epithelial reticular cells of the thymus and the regulatory T-lymphocytes
title_full_unstemmed Epithelial reticular cells of the thymus and the regulatory T-lymphocytes
title_short Epithelial reticular cells of the thymus and the regulatory T-lymphocytes
title_sort epithelial reticular cells of the thymus and the regulatory t lymphocytes
topic thymus
reticular epithelial cells
regulatory t-cells
tolerance
url https://www.sechenovmedj.com/jour/article/view/681
work_keys_str_mv AT vetorbek epithelialreticularcellsofthethymusandtheregulatorytlymphocytes
AT slkuznetsov epithelialreticularcellsofthethymusandtheregulatorytlymphocytes