A pre-clinical MRI-guided all-in-one focused ultrasound system for murine brain studies

A pre-clinical MRI-guided all-in-one focused ultrasound system for murine brain studies

Abstract This paper describes the design and initial proof-of-concept of a single pre-clinical transcranial focused ultrasound (FUS) system capable of performing histotripsy (mechanical ablation), hyperthermia, blood-brain barrier opening (BBBO), sonodynamic therapy, or neuromodulation in a murine b...

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Bibliographic Details
Main Authors: Tarana Parvez Kaovasia, Sarah Duclos, Dinank Gupta, Kourosh Kalayeh, Mario Fabiilli, Douglas C. Noll, Jonathan Sukovich, Aditya Pandey, Zhen Xu, Timothy L. Hall
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Therapeutic ultrasound
Brain
Histotripsy
Blood-brain barrier opening
Hyperthermia
Magnetic resonance imaging (MRI)
Online Access:https://doi.org/10.1038/s41598-024-84078-9
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