A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis
Hui-Juan Li, Yue-Ying Zhou, He-He Yu, Jian Jiang, Yu-Wei Cai Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, People’s Republic of ChinaCorrespondence: Yue-Ying Zhou, Department of Infectious Diseases, Wenzhou Central Hospital, No. 252 Baili East Road, Lucheng District, Wenzhou...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2025-01-01
|
| Series: | Clinical Interventions in Aging |
| Subjects: | |
| Online Access: | https://www.dovepress.com/a-preliminary-screening-tool-for-high-risk-frailty-in-older-adults-pat-peer-reviewed-fulltext-article-CIA |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832590407405404160 |
|---|---|
| author | Li HJ Zhou YY Yu HH Jiang J Cai YW |
| author_facet | Li HJ Zhou YY Yu HH Jiang J Cai YW |
| author_sort | Li HJ |
| collection | DOAJ |
| description | Hui-Juan Li, Yue-Ying Zhou, He-He Yu, Jian Jiang, Yu-Wei Cai Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, People’s Republic of ChinaCorrespondence: Yue-Ying Zhou, Department of Infectious Diseases, Wenzhou Central Hospital, No. 252 Baili East Road, Lucheng District, Wenzhou City, 325000, People’s Republic of China, Tel +86-0577-88882121, Email zhouyueying25@163.comObjective: To understand the current status and analyse the factors influencing frailty in older adults patients with pulmonary tuberculosis.Methods: This retrospective case-control study included 204 older adults patients with pulmonary tuberculosis. The enrolled patients were divided into a frailty group (n = 101) and a non-frailty group (n = 103). The study further collected and compared the data of various scores.Results: The total frailty score among the patients ranged from 0 to 15 points, with an average score of 5.23 ± 2.31 points. The total social support score ranged from 15 to 47 points, with an average of 33.43 ± 6.11 points. The physical function level scores ranged from 10 to 100 points, with an average of 84.58 ± 14.48 points. Additionally, univariate analysis showed significant differences between the groups in terms of age, body mass index (BMI), duration of disease, types of long-term medication and the number of complications and comorbidities (P < 0.05). Correlation analysis revealed negative correlations of social support (P < 0.001) and physical function (P < 0.001) with the overall frailty score and a positive correlation of depression levels (P < 0.001) with the overall frailty score. Further regression analysis indicated that being over 80 years old, having a low BMI, long-term polypharmacy and a high depression score were risk factors. High social support and physical function scores were protective factors against frailty in older adults patients with pulmonary tuberculosis.Conclusion: In older adults patients with pulmonary tuberculosis, the overall frailty score shows negative correlations with social support and physical function and a positive correlation with depression level.Keywords: pulmonary tuberculosis, frailty, older adults, risk factors |
| format | Article |
| id | doaj-art-900cbd8060914ecab8c1f77dd2e7e23b |
| institution | Kabale University |
| issn | 1178-1998 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Interventions in Aging |
| spelling | doaj-art-900cbd8060914ecab8c1f77dd2e7e23b2025-01-23T18:50:33ZengDove Medical PressClinical Interventions in Aging1178-19982025-01-01Volume 20576899500A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary TuberculosisLi HJZhou YYYu HHJiang JCai YWHui-Juan Li, Yue-Ying Zhou, He-He Yu, Jian Jiang, Yu-Wei Cai Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, People’s Republic of ChinaCorrespondence: Yue-Ying Zhou, Department of Infectious Diseases, Wenzhou Central Hospital, No. 252 Baili East Road, Lucheng District, Wenzhou City, 325000, People’s Republic of China, Tel +86-0577-88882121, Email zhouyueying25@163.comObjective: To understand the current status and analyse the factors influencing frailty in older adults patients with pulmonary tuberculosis.Methods: This retrospective case-control study included 204 older adults patients with pulmonary tuberculosis. The enrolled patients were divided into a frailty group (n = 101) and a non-frailty group (n = 103). The study further collected and compared the data of various scores.Results: The total frailty score among the patients ranged from 0 to 15 points, with an average score of 5.23 ± 2.31 points. The total social support score ranged from 15 to 47 points, with an average of 33.43 ± 6.11 points. The physical function level scores ranged from 10 to 100 points, with an average of 84.58 ± 14.48 points. Additionally, univariate analysis showed significant differences between the groups in terms of age, body mass index (BMI), duration of disease, types of long-term medication and the number of complications and comorbidities (P < 0.05). Correlation analysis revealed negative correlations of social support (P < 0.001) and physical function (P < 0.001) with the overall frailty score and a positive correlation of depression levels (P < 0.001) with the overall frailty score. Further regression analysis indicated that being over 80 years old, having a low BMI, long-term polypharmacy and a high depression score were risk factors. High social support and physical function scores were protective factors against frailty in older adults patients with pulmonary tuberculosis.Conclusion: In older adults patients with pulmonary tuberculosis, the overall frailty score shows negative correlations with social support and physical function and a positive correlation with depression level.Keywords: pulmonary tuberculosis, frailty, older adults, risk factorshttps://www.dovepress.com/a-preliminary-screening-tool-for-high-risk-frailty-in-older-adults-pat-peer-reviewed-fulltext-article-CIApulmonary tuberculosisfrailtyolder adultsrisk factors |
| spellingShingle | Li HJ Zhou YY Yu HH Jiang J Cai YW A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis Clinical Interventions in Aging pulmonary tuberculosis frailty older adults risk factors |
| title | A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis |
| title_full | A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis |
| title_fullStr | A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis |
| title_full_unstemmed | A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis |
| title_short | A Preliminary Screening Tool for High-Risk Frailty in Older Adults Patients with Pulmonary Tuberculosis |
| title_sort | preliminary screening tool for high risk frailty in older adults patients with pulmonary tuberculosis |
| topic | pulmonary tuberculosis frailty older adults risk factors |
| url | https://www.dovepress.com/a-preliminary-screening-tool-for-high-risk-frailty-in-older-adults-pat-peer-reviewed-fulltext-article-CIA |
| work_keys_str_mv | AT lihj apreliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT zhouyy apreliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT yuhh apreliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT jiangj apreliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT caiyw apreliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT lihj preliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT zhouyy preliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT yuhh preliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT jiangj preliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis AT caiyw preliminaryscreeningtoolforhighriskfrailtyinolderadultspatientswithpulmonarytuberculosis |