The SAMD1 transcription factor coordinates hematopoietic lineage differentiation and H3K4 methylation status

The SAMD1 transcription factor coordinates hematopoietic lineage differentiation and H3K4 methylation status

Abstract: Cell progenitor to progeny transitions depend on precise transcriptional mechanisms to adjust gene expression. The sterile α-motif–containing 1 protein (SAMD1) regulates a shift in transcriptional activity during embryonic stem cell exit from pluripotency. SAMD1 interacts with, and facilit...

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Main Authors: Meg A. Schaefer, Samantha L. Gomez, Venkatasai Rahul Dogiparthi, Yichao Zhou, Pooja Roy, Suhita Ray, Linda Chee, Sandipan Brahma, Robert Liefke, Kyle J. Hewitt
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925002964
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