The Synthesis of 2,5-Dioxaspiro[3.4]octane Building Blocks: Three-Dimensional Spirocyclic Analogs of 1,4-Dioxanes
A ring-closing metathesis (RCM) strategy was employed for the synthesis of spirooxetane compounds with a tetrahydrofuran (THF) core. The approach proposed relied on the preparation of an unsaturated spirooxetane from vinyl oxetanol. The reaction sequence involved the NaH-mediated О-alkylation with m...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy (Kharkiv)
2025-04-01
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| Series: | Журнал органічної та фармацевтичної хімії |
| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/324901 |
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