Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature

Epithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic tumor. Cases of ETT present as abnormal vaginal bleeding in women of reproductive age, with low human chorionic gonadotropin (hCG) levels. ETT can be a sequela of any gestational event and can present in both intrauterine and...

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Main Authors: Eirwen M. Scott, Ashlee L. Smith, Mohamed Mokhtar Desouki, Alexander B. Olawaiye
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2012/862472
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author Eirwen M. Scott
Ashlee L. Smith
Mohamed Mokhtar Desouki
Alexander B. Olawaiye
author_facet Eirwen M. Scott
Ashlee L. Smith
Mohamed Mokhtar Desouki
Alexander B. Olawaiye
author_sort Eirwen M. Scott
collection DOAJ
description Epithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic tumor. Cases of ETT present as abnormal vaginal bleeding in women of reproductive age, with low human chorionic gonadotropin (hCG) levels. ETT can be a sequela of any gestational event and can present in both intrauterine and extrauterine sites. Metastasis and death have been reported. We present a case of a 44-year-old female incidentally diagnosed with ETT following laparoscopic-assisted vaginal hysterectomy. Postoperative evaluation for metastatic disease was negative. The patient has been closely followed and remains disease free 8 months postoperatively. ETT presents a diagnostic challenge due to its rarity and histologic resemblance to other pathologies. ETT is relatively chemoresistant and managed surgically. Misdiagnosis delays effective treatment and affects survival.
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-8ff3fe8452e2431389a9f37d27e23f452025-02-03T01:07:46ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922012-01-01201210.1155/2012/862472862472Epithelioid Trophoblastic Tumor: A Case Report and Review of the LiteratureEirwen M. Scott0Ashlee L. Smith1Mohamed Mokhtar Desouki2Alexander B. Olawaiye3Department of Gynecologic Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USADepartment of Gynecologic Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USADepartment of Pathology, Breast, and Gynecologic Pathology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USADepartment of Gynecologic Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USAEpithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic tumor. Cases of ETT present as abnormal vaginal bleeding in women of reproductive age, with low human chorionic gonadotropin (hCG) levels. ETT can be a sequela of any gestational event and can present in both intrauterine and extrauterine sites. Metastasis and death have been reported. We present a case of a 44-year-old female incidentally diagnosed with ETT following laparoscopic-assisted vaginal hysterectomy. Postoperative evaluation for metastatic disease was negative. The patient has been closely followed and remains disease free 8 months postoperatively. ETT presents a diagnostic challenge due to its rarity and histologic resemblance to other pathologies. ETT is relatively chemoresistant and managed surgically. Misdiagnosis delays effective treatment and affects survival.http://dx.doi.org/10.1155/2012/862472
spellingShingle Eirwen M. Scott
Ashlee L. Smith
Mohamed Mokhtar Desouki
Alexander B. Olawaiye
Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature
Case Reports in Obstetrics and Gynecology
title Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature
title_full Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature
title_fullStr Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature
title_full_unstemmed Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature
title_short Epithelioid Trophoblastic Tumor: A Case Report and Review of the Literature
title_sort epithelioid trophoblastic tumor a case report and review of the literature
url http://dx.doi.org/10.1155/2012/862472
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AT mohamedmokhtardesouki epithelioidtrophoblastictumoracasereportandreviewoftheliterature
AT alexanderbolawaiye epithelioidtrophoblastictumoracasereportandreviewoftheliterature