Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice

Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice

The purinergic P2X7 receptor is expressed by bone cells and has been shown to be important in both bone formation and bone resorption. In this study we investigated the importance of the genetic background of the mouse strains on which the P2X7 knock-out models were based by comparing bone status of...

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Bibliographic Details
Main Authors: Susanne Syberg, Solveig Petersen, Jens-Erik Beck Jensen, Alison Gartland, Jenni Teilmann, Iain Chessell, Thomas H. Steinberg, Peter Schwarz, Niklas Rye Jørgensen
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Osteoporosis
Online Access:http://dx.doi.org/10.1155/2012/391097
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