Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study
Background: Map-dot-fingerprint (MDF) is a corneal epithelial dystrophy affecting the basement membrane that presents bilaterally or in an asymmetric manner. Clinically, it appears as opacities or fingerprint lines and histopathologically, microcystic structures, dot-like patterns, or basement membr...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | The Pan-American Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/pajo.pajo_90_24 |
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| _version_ | 1841537328060825600 |
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| author | Emily Marcotte Pedro Fraiha Angela Fajardo Devinder Cheema Mahshad Darvish Miguel Noel Burnier |
| author_facet | Emily Marcotte Pedro Fraiha Angela Fajardo Devinder Cheema Mahshad Darvish Miguel Noel Burnier |
| author_sort | Emily Marcotte |
| collection | DOAJ |
| description | Background:
Map-dot-fingerprint (MDF) is a corneal epithelial dystrophy affecting the basement membrane that presents bilaterally or in an asymmetric manner. Clinically, it appears as opacities or fingerprint lines and histopathologically, microcystic structures, dot-like patterns, or basement membrane thickening are commonly described features.
Materials and Methods:
We conducted a retrospective study on 10 cases of MDF obtained from 9 patients between 2017 to 2018 from the MUHC-McGill Ocular Pathology & Translational Research Laboratory.
Results:
Following histopathological evaluation with hematoxylin and eosin, periodic acid–Schiff (PAS), and in one case Alcian Blue, a final diagnosis of MDF was reached in all cases.
Conclusion:
This case series aims to document MDFs histopathological characteristics. To the best of our knowledge, this is the largest case series with histopathological diagnosis published, filling an important gap in the literature. |
| format | Article |
| id | doaj-art-8ff2ab076e3046658c1fdd1ec545ebb4 |
| institution | Kabale University |
| issn | 2666-4909 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Pan-American Journal of Ophthalmology |
| spelling | doaj-art-8ff2ab076e3046658c1fdd1ec545ebb42025-01-14T08:39:46ZengWolters Kluwer Medknow PublicationsThe Pan-American Journal of Ophthalmology2666-49092024-12-0163444410.4103/pajo.pajo_90_24Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological studyEmily MarcottePedro FraihaAngela FajardoDevinder CheemaMahshad DarvishMiguel Noel BurnierBackground: Map-dot-fingerprint (MDF) is a corneal epithelial dystrophy affecting the basement membrane that presents bilaterally or in an asymmetric manner. Clinically, it appears as opacities or fingerprint lines and histopathologically, microcystic structures, dot-like patterns, or basement membrane thickening are commonly described features. Materials and Methods: We conducted a retrospective study on 10 cases of MDF obtained from 9 patients between 2017 to 2018 from the MUHC-McGill Ocular Pathology & Translational Research Laboratory. Results: Following histopathological evaluation with hematoxylin and eosin, periodic acid–Schiff (PAS), and in one case Alcian Blue, a final diagnosis of MDF was reached in all cases. Conclusion: This case series aims to document MDFs histopathological characteristics. To the best of our knowledge, this is the largest case series with histopathological diagnosis published, filling an important gap in the literature.https://journals.lww.com/10.4103/pajo.pajo_90_24corneal dystrophyepithelial basement membrane dystrophyhistopathologymap-dot-fingerprint dystrophy |
| spellingShingle | Emily Marcotte Pedro Fraiha Angela Fajardo Devinder Cheema Mahshad Darvish Miguel Noel Burnier Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study The Pan-American Journal of Ophthalmology corneal dystrophy epithelial basement membrane dystrophy histopathology map-dot-fingerprint dystrophy |
| title | Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study |
| title_full | Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study |
| title_fullStr | Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study |
| title_full_unstemmed | Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study |
| title_short | Map-dot-fingerprint (epithelial basement membrane) corneal dystrophy: A clinicopathological study |
| title_sort | map dot fingerprint epithelial basement membrane corneal dystrophy a clinicopathological study |
| topic | corneal dystrophy epithelial basement membrane dystrophy histopathology map-dot-fingerprint dystrophy |
| url | https://journals.lww.com/10.4103/pajo.pajo_90_24 |
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