Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy
Introduction: Patients treated in the intensive care unit (ICU) are usually patients who deteriorated health condition and could have longer hospital stay compared to other patients. Hospital infections are more common in ICU patients. The aim of this study was to evaluate the bacteria and treatmen...
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The Journal of Infection in Developing Countries
2020-08-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/12219 |
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| author | Duygu Mert Selda Muslu Alparslan Merdin Arif Timuroğlu Ece Dirim Süheyla Ünver Mustafa Ertek |
| author_facet | Duygu Mert Selda Muslu Alparslan Merdin Arif Timuroğlu Ece Dirim Süheyla Ünver Mustafa Ertek |
| author_sort | Duygu Mert |
| collection | DOAJ |
| description |
Introduction: Patients treated in the intensive care unit (ICU) are usually patients who deteriorated health condition and could have longer hospital stay compared to other patients. Hospital infections are more common in ICU patients. The aim of this study was to evaluate the bacteria and treatment resistance profiles isolated from clinical specimens sent for hospital infections in ICU patients between January 1, 2014 and December 31, 2018.
Methodology: Bacteria isolated from various clinical samples sent for hospital infections in hospitalized patients in the Anesthesia and Reanimation Intensive Care Unit were retrospectively analyzed.
Results: Culture positivity was detected in 547 of the sent clinical samples. Eighty Gram-positive bacteria, 389 Gram-negative bacteria and 78 fungi infection were identified in a total of 547 positive cultures. In Gram-positive bacteria, 4 MRSA, 6 VRE and 30 MRCoNS were identified as resistant strains. In Gram-negative bacteria, Acinetobacter spp. was the most culture positive strain with the number of 223. Carbapenem resistance was found in 258 of the Gram-negative bacteria and ESBL positivity was found in 44 of the Gram-negative bacteria strains.
Conclusions: Gram-negative bacteria were the most frequently isolated strain in samples. Recently, colistin resistance has been increasing in Acinetobacter spp. and the increase in carbapenemase enzyme in Escherichia coli, Pseudomonas and Klebsiella species has increased resistance to carbapenems. Knowing the microorganisms that grow in ICUs and their antibiotic resistance patterns may help to prevent contamination of resistant microorganisms by both appropriate empirical antibiotic treatment and more isolation as well as general hygiene standard precautions.
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| format | Article |
| id | doaj-art-8fea73fce75343c3ab4e8767528dd471 |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2020-08-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-8fea73fce75343c3ab4e8767528dd4712025-08-20T02:57:01ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802020-08-01140810.3855/jidc.12219Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancyDuygu Mert0Selda Muslu1Alparslan Merdin2Arif Timuroğlu3Ece Dirim4Süheyla Ünver5Mustafa Ertek6Infectious Diseases and Clinical Microbiology Clinic, University of Health Sciences Dr.Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, TurkeyAnesthesia and Reanimation Intensive Care Unit, University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, TurkeyHematology Clinic and Bone Marrow Transplantation Unit, University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, TurkeyAnesthesia and Reanimation Intensive Care Unit, University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, TurkeyMedical Microbiology Laboratory, University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, TurkeyAnesthesia and Reanimation Intensive Care Unit, University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, TurkeyInfectious Diseases and Clinical Microbiology Clinic, University of Health Sciences Dr.Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey Introduction: Patients treated in the intensive care unit (ICU) are usually patients who deteriorated health condition and could have longer hospital stay compared to other patients. Hospital infections are more common in ICU patients. The aim of this study was to evaluate the bacteria and treatment resistance profiles isolated from clinical specimens sent for hospital infections in ICU patients between January 1, 2014 and December 31, 2018. Methodology: Bacteria isolated from various clinical samples sent for hospital infections in hospitalized patients in the Anesthesia and Reanimation Intensive Care Unit were retrospectively analyzed. Results: Culture positivity was detected in 547 of the sent clinical samples. Eighty Gram-positive bacteria, 389 Gram-negative bacteria and 78 fungi infection were identified in a total of 547 positive cultures. In Gram-positive bacteria, 4 MRSA, 6 VRE and 30 MRCoNS were identified as resistant strains. In Gram-negative bacteria, Acinetobacter spp. was the most culture positive strain with the number of 223. Carbapenem resistance was found in 258 of the Gram-negative bacteria and ESBL positivity was found in 44 of the Gram-negative bacteria strains. Conclusions: Gram-negative bacteria were the most frequently isolated strain in samples. Recently, colistin resistance has been increasing in Acinetobacter spp. and the increase in carbapenemase enzyme in Escherichia coli, Pseudomonas and Klebsiella species has increased resistance to carbapenems. Knowing the microorganisms that grow in ICUs and their antibiotic resistance patterns may help to prevent contamination of resistant microorganisms by both appropriate empirical antibiotic treatment and more isolation as well as general hygiene standard precautions. https://jidc.org/index.php/journal/article/view/12219Gram-negative bacteriaGram-positive bacteriafungusICU |
| spellingShingle | Duygu Mert Selda Muslu Alparslan Merdin Arif Timuroğlu Ece Dirim Süheyla Ünver Mustafa Ertek Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy Journal of Infection in Developing Countries Gram-negative bacteria Gram-positive bacteria fungus ICU |
| title | Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy |
| title_full | Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy |
| title_fullStr | Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy |
| title_full_unstemmed | Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy |
| title_short | Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy |
| title_sort | five year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy |
| topic | Gram-negative bacteria Gram-positive bacteria fungus ICU |
| url | https://jidc.org/index.php/journal/article/view/12219 |
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