[68Ga] labelled Exendin for radioguided surgery of intrapancreatic insulin producing lesions in patients with congenital hyperinsulinism

[68Ga] labelled Exendin for radioguided surgery of intrapancreatic insulin producing lesions in patients with congenital hyperinsulinism

Abstract Background Congenital hyperinsulinism (CHI) is a life threatening disease. Localization of affected intrapancreatic beta cells responsible for focal forms during surgery can be challenging. In this study we investigated a new radioguided surgical (RGS) approach using [68Ga]Exendin to facili...

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Main Authors: Peter Kühnen, Sonal Prasad, Karin Rothe, Kai Huang, Kathrin Hauptmann, Marti Boss, Nicola Beindorff, Erwin Lankes, Steven W. Warmann, Miriam Schneider, Paniz Akbarzadeh Taghavi, Lara Lechner, Catharina Lange, Christian Furth, Martin Gotthardt, Winfried Brenner, Oliver Blankenstein, Vikas Prasad
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:EJNMMI Research
Subjects:
[68Ga]Exendin-NODAGA
Congenital hyperinsulinism
Radioguided surgery
Online Access:https://doi.org/10.1186/s13550-025-01294-8
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