Stronger binding affinities of gp120/CD4 in Catarrhini provide insights into HIV/host interactions

Human immunodeficiency virus-1 (HIV-1) exploits the viral gp120 protein and host CD4/CCR5 receptors for the pandemic infection to humans. The host co-receptors of not only humans but also several primates and HIV-model mice can interact with the HIV receptor. However, the molecular mechanisms of the...

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Bibliographic Details
Main Authors: Vladimir Li, Chul Lee, TaeHyun Park, Erich D. Jarvis, Heebal Kim
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Infectious Disease Modelling
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468042724001180
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