Rbfox3 Promotes Transformation of MDSC‐Like Tumor Cells to Shape Immunosuppressive Microenvironment

Rbfox3 Promotes Transformation of MDSC‐Like Tumor Cells to Shape Immunosuppressive Microenvironment

Abstract Myeloid‐derived suppressor cells (MDSCs) within the tumor microenvironment (TME) contribute to the malignant progression of tumors by exerting immunosuppressive effects. Bacterial lipopolysaccharides (LPS) have been widely demonstrated in various types of solid tumors. LPS can promote the m...

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Main Authors: Zhiyang Li, Zhuangzhuang Feng, Mengzhan Chen, Xinxiu Shi, Bijia Cui, Yujie Sun, Heng Zhang, Yinan Li, Caihong Chen, Yiqian Feng, Jingxia Han, Xuewu Xing, Huijuan Liu, Tao Sun
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
immunosuppressive tumor microenvironment
MDSC‐like tumor cells
phase‐separated particles
Rbfox3
Online Access:https://doi.org/10.1002/advs.202404585
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