Rapid and Efficient Synthesis of Succinated Thiol Compounds via Maleic Anhydride Derivatization
Succination is a non-enzymatic post-translational modification of cysteine (Cys) residues, resulting in the formation of <i>S</i>-(2-succino)cysteine (2SC). While hundreds of 2SC-modified proteins have been identified and are associated with the dysfunction of proteins, the underlying mo...
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| Main Authors: | Hiroshi Yamaguchi, Hikari Sugawa, Himeno Takahashi, Ryoji Nagai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/30/3/571 |
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