Hybrid Sindbis/Epstein-Barr virus episomal expression vector for inducible production of proteins
Alphavirus vectors are attractive as recombinant protein expression systems due to the high level of gene expression achieved. The combination of two mutations in the viral replicase, which render the replicase noncytopathic and temperature-sensitive, allowed the generation of a DNA-based vector (Cy...
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| Main Authors: | Lidia Ivanova, Johanna Brändli, Philippe Saudan, Martin F. Bachmann |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2005-08-01
|
| Series: | BioTechniques |
| Online Access: | https://www.future-science.com/doi/10.2144/05392ST03 |
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