The contributions of interlocking loops and extensive nonlinearity to the properties of circadian clock models.

The contributions of interlocking loops and extensive nonlinearity to the properties of circadian clock models.

<h4>Background</h4>Sensitivity and robustness are essential properties of circadian clock systems, enabling them to respond to the environment but resist noisy variations. These properties should be recapitulated in computational models of the circadian clock. Highly nonlinear kinetics a...

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Bibliographic Details
Main Authors: Treenut Saithong, Kevin J Painter, Andrew J Millar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013867&type=printable
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