A Natural Latex-Based Smart Dressing for Curcumin Delivery Combined with LED Phototherapy in Diabetic Foot Ulcers: A Pilot Clinical Study

A Natural Latex-Based Smart Dressing for Curcumin Delivery Combined with LED Phototherapy in Diabetic Foot Ulcers: A Pilot Clinical Study

<b>Background</b>: Diabetic foot ulcers (DFUs) affect 25% of diabetes patients, with high risks of amputation (70%), recurrence (65% within 3–5 years), and mortality (50–70% at 5-years). Current treatments are limited by persistent inflammation, oxidative stress, and cost barriers. This...

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Main Authors: Thamis Fernandes Santana Gomes, Natália Carvalho Guimarães, Ludmilla Pinto Guiotti Cintra Abreu, Gabriella de Oliveira Silva, Vitória Regina Pereira da Silva, Franciéle de Matos da Silva, Fabiane Hiratsuka Veiga-Souza, Paulo Eduardo Narcizo de Souza, Mário Fabrício Fleury Rosa, Graziella Anselmo Joanitti, Suélia de Siqueira Rodrigues Fleury Rosa, Marcella Lemos Brettas Carneiro
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceutics
Subjects:
curcumin
natural latex biomembrane
wound healing
ulcers
oxidative stress
clinical assay
Online Access:https://www.mdpi.com/1999-4923/17/6/772
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