Discovery of Biofilm-Inhibiting Compounds to Enhance Antibiotic Effectiveness Against <i>M. abscessus</i> Infections

Discovery of Biofilm-Inhibiting Compounds to Enhance Antibiotic Effectiveness Against <i>M. abscessus</i> Infections

<b>Background/Objectives</b>: <i>Mycobacterium abscessus</i> (MAB) is a highly resilient pathogen that causes difficult-to-treat pulmonary infections, particularly in individuals with cystic fibrosis (CF) and other underlying conditions. Its ability to form robust biofilms wi...

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Bibliographic Details
Main Authors: Elizaveta Dzalamidze, Mylene Gorzynski, Rebecca Vande Voorde, Dylan Nelson, Lia Danelishvili
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
<i>Mycobacterium abscessus</i>
nontuberculous mycobacteria
NTM
high-throughput screening
small molecules
biofilm
Online Access:https://www.mdpi.com/1424-8247/18/2/225
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