Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa

Background. There are only a few comprehensive studies of adherence to ART and its challenges in Africa. This paper aims to assess the evidence on the challenges and prospects of ART adherence in sub-Saharan Africa. Methods. The authors reviewed original and review articles involving HIV-positive in...

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Main Authors: Ayalu A. Reda, Sibhatu Biadgilign
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:AIDS Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/574656
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author Ayalu A. Reda
Sibhatu Biadgilign
author_facet Ayalu A. Reda
Sibhatu Biadgilign
author_sort Ayalu A. Reda
collection DOAJ
description Background. There are only a few comprehensive studies of adherence to ART and its challenges in Africa. This paper aims to assess the evidence on the challenges and prospects of ART adherence in sub-Saharan Africa. Methods. The authors reviewed original and review articles involving HIV-positive individuals that measured adherence to ART and its predictors in the past decade. Findings. Against expectations, sub-Saharan Africa patients have similar or higher adherence levels compared to those of developed countries. The challenges to ART adherence include factors related to patients and their families, socioeconomic factors, medication, and healthcare systems. Conclusion. Despite good adherence and program-related findings, antiretroviral treatment is challenged by a range of hierarchical and interrelated factors. There is substantial room for improvement of ART programs in sub-Sahara African countries.
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spelling doaj-art-8fb266befd8f4ad98e99e7df1ea9291d2025-08-20T03:36:59ZengWileyAIDS Research and Treatment2090-12402090-12592012-01-01201210.1155/2012/574656574656Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in AfricaAyalu A. Reda0Sibhatu Biadgilign1Department of Public Health, College of Health Sciences, Haramaya University, P.O. Box 1014, Harar, EthiopiaDepartment of Epidemiology and Biostatistics, Jimma University, P.O. Box 24414, Jimma, EthiopiaBackground. There are only a few comprehensive studies of adherence to ART and its challenges in Africa. This paper aims to assess the evidence on the challenges and prospects of ART adherence in sub-Saharan Africa. Methods. The authors reviewed original and review articles involving HIV-positive individuals that measured adherence to ART and its predictors in the past decade. Findings. Against expectations, sub-Saharan Africa patients have similar or higher adherence levels compared to those of developed countries. The challenges to ART adherence include factors related to patients and their families, socioeconomic factors, medication, and healthcare systems. Conclusion. Despite good adherence and program-related findings, antiretroviral treatment is challenged by a range of hierarchical and interrelated factors. There is substantial room for improvement of ART programs in sub-Sahara African countries.http://dx.doi.org/10.1155/2012/574656
spellingShingle Ayalu A. Reda
Sibhatu Biadgilign
Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa
AIDS Research and Treatment
title Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa
title_full Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa
title_fullStr Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa
title_full_unstemmed Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa
title_short Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa
title_sort determinants of adherence to antiretroviral therapy among hiv infected patients in africa
url http://dx.doi.org/10.1155/2012/574656
work_keys_str_mv AT ayaluareda determinantsofadherencetoantiretroviraltherapyamonghivinfectedpatientsinafrica
AT sibhatubiadgilign determinantsofadherencetoantiretroviraltherapyamonghivinfectedpatientsinafrica